Evidence map›Paper›PMID 32272689›Full record

ArticleInternational journal of molecular sciences2020

Benzylaminoethyureido-Tailed Benzenesulfonamides: Design, Synthesis, Kinetic and X-ray Investigations on Human Carbonic Anhydrases.

Majid Ali, Murat Bozdag, Umar Farooq, Andrea Angeli, Fabrizio Carta, Paola Berto, Giuseppe Zanotti, Claudiu T Supuran

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Carbonic Anhydrases: A Superfamily of Ubiquitous Enzymes.International journal of molecular sciences · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Majid AliDipartimento Neurofarba, Università degli Studi di Firenze, Sezione di Scienze Farmaceutiche, Polo Scientifico, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.ORCID 0000-0002-6873-0953
Murat BozdagDipartimento Neurofarba, Università degli Studi di Firenze, Sezione di Scienze Farmaceutiche, Polo Scientifico, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.ORCID 0000-0002-5010-0355
Umar FarooqDepartment of Chemistry, COMSATS University Islamabad, Abbottabad Campus, KPK 22060, Islamabad 45550, Pakistan.ORCID 0000-0001-5557-2776
Andrea AngeliDipartimento Neurofarba, Università degli Studi di Firenze, Sezione di Scienze Farmaceutiche, Polo Scientifico, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.ORCID 0000-0002-1470-7192
Fabrizio CartaDipartimento Neurofarba, Università degli Studi di Firenze, Sezione di Scienze Farmaceutiche, Polo Scientifico, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.ORCID 0000-0002-1141-6146
Paola BertoDepartment of Biomedical Sciences, Università di Padova, Via Ugo Bassi 58/B, 35131 Padua, Italy.
Giuseppe ZanottiDepartment of Biomedical Sciences, Università di Padova, Via Ugo Bassi 58/B, 35131 Padua, Italy.
Claudiu T SupuranDipartimento Neurofarba, Università degli Studi di Firenze, Sezione di Scienze Farmaceutiche, Polo Scientifico, Via Ugo Schiff 6, Sesto Fiorentino, 50019 Florence, Italy.ORCID 0000-0003-4262-0323

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A drug design strategy of carbonic anhydrase inhibitors (CAIs) belonging to sulfonamides incorporating ureidoethylaminobenzyl tails is presented. A variety of substitution patterns on the ring and the tails, located on

Indexed as

BenzenesulfonamidesCarbonic Anhydrase InhibitorsCarbonic AnhydrasesCrystallography, X-RayDrug DesignHumansKineticsProtein IsoformsStructure-Activity RelationshipSulfonamidesX-RaysBenzenesulfonamidesCarbonic Anhydrase InhibitorsCarbonic AnhydrasesProtein IsoformsSulfonamidescarbonic anhydrase: sulfonamidetail approachX-ray crystallography

Identifiers

PMID32272689
PMCPMC7177897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.