ArticleJournal of theoretical biology2020
Modeling the waning and boosting of immunity from infection or vaccination.
Article in Journal of theoretical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 43 citations in OpenAlex.
- Prior pathogen exposure augments inter-individual heterogeneity in antibody levels and reinfection loads in a songbird-pathogen system.Scientific reports · 2026Article
- Leaky or polarised immunity: Non-Markovian modelling highlights the impact of immune memory assumptions.PLoS computational biology · 2025Article
- Reinfection with a Bacterial Pathogen Augments Heterogeneity in Host Disease Responses.Research square · 2025Article
- Optimal vaccination policy to prevent endemicity: a stochastic model.Journal of mathematical biology · 2024Article
- Deterministic modelling of asymptomatic spread and disease stage progression in vaccine preventable infectious diseases.Quantitative biology (Beijing, China) · 2024Article
- Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences.PLoS pathogens · 2024Article
- Prior exposure to pathogens augments host heterogeneity in susceptibility and has key epidemiological consequences.bioRxiv : the preprint server for biology · 2024Article
- An Epidemic Model with Infection Age and Vaccination Age Structure.Infectious disease reports · 2024Article
- Effects of boosting and waning in highly exposed populations on dengue epidemic dynamics.Science translational medicine · 2023Article
- Extending susceptible-infectious-recovered-susceptible epidemics to allow for gradual waning of immunity.Journal of the Royal Society, Interface · 2023Article
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- The impact of cross-reactive immunity on the emergence of SARS-CoV-2 variants.Frontiers in immunology · 2022Article
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- Article
- One Dimensional Reduction of a Renewal Equation for a Measure-Valued Function of Time Describing Population Dynamics.Acta applicandae mathematicae · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 7 institutions in 4 countries.
Funding
Abstract
Immunity following natural infection or immunization may wane, increasing susceptibility to infection with time since infection or vaccination. Symptoms, and concomitantly infectiousness, depend on residual immunity. We quantify these phenomena in a model population composed of individuals whose susceptibility, infectiousness, and symptoms all vary with immune status. We also model age, which affects contact, vaccination and possibly waning rates. The resurgences of pertussis that have been observed wherever effective vaccination programs have reduced typical disease among young children follow from these processes. As one example, we compare simulations with the experience of Sweden following resumption of pertussis vaccination after the hiatus from 1979 to 1996, reproducing the observations leading health authorities to introduce booster doses among school-aged children and adolescents in 2007 and 2014, respectively. Because pertussis comprises a spectrum of symptoms, only the most severe of which are medically attended, accurate models are needed to design optimal vaccination programs where surveillance is less effective.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.