Evidence map›Paper›PMID 32271993›Full record

ArticleObesity (Silver Spring, Md.)2020

High Prevalence of Obesity in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) Requiring Invasive Mechanical Ventilation.

Arthur Simonnet, Mikael Chetboun, Julien Poissy, Violeta Raverdy, Jerome Noulette, Alain Duhamel, Julien Labreuche, Daniel Mathieu, Francois Pattou, Merce Jourdain and 1 more

Erratum issued 3 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Obesity (Silver Spring, Md.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 3 registered trials, which are not on this map. Cited by 1,123 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,123citing papers in PubMed, 9 pooled it
51.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04459390 unknown statusnot on this map

Impact of Comorbidities on COVID19 Outcome

TypeobservationalSponsorAssiut UniversityRan2020 to 2020Enrolled100ConditionsCOVID19Armsrealtime PCR
NCT04670094 completednot on this map

Comorbidities and Risk Score for Severity and Outcome in Patients With Infection by SARS-CoV-2.

TypeobservationalSponsorUniversity of Milano BicoccaRan2020 to 2021Enrolled4,555ConditionsCovid19
NCT05771857 completednot on this map

Obesity: an Underappreciate Risk Factor for Severe Form of COVID-19: Retrospective Cohort Study of 415 Cases

Typeobservational_patient_registrySponsorMohammed VI University HospitalRan2020 to 2021Enrolled415ConditionsCOVID-19 Pandemic, ObesityArmsObesity
3 · Its place in the literature

Who cites it

1,123 citing papers in PubMed, 9 syntheses or guidelines pooled it, 2,161 citations in OpenAlex.

  1. Pooled it
  2. PROKR1-CREB-NR4A2 axis for oxidative muscle fiber specification and improvement of metabolic function.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Pooled it
  3. Pooled it
  4. Pediatric endocrinopathies related to COVID-19: an update.World journal of pediatrics : WJP · 2023
    Pooled it
  5. Obesity as an independent risk factor for COVID-19 severity and mortality.The Cochrane database of systematic reviews · 2023
    Pooled it
  6. Pooled it
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  12. Observational
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  15. Tracking Sarcopenia and Physical Activities Among Korean Adults Aged 50 Years and Older During COVID-19 Pandemic.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Article
  16. Article
  17. Non-communicable diseases, COVID-19 and labour market outcomes.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Article
  18. Review
  19. Risk factors for death by COVID-19, public hospital in Ciudad Juárez, México.Revista medica del Instituto Mexicano del Seguro Social · 2026
    Observational
  20. Article

1,063 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Arthur Simonnet *Department of Intensive Care, Centre Hospitalier Universitaire Lille, Lille, France.
Mikael Chetboun *University of Lille, Inserm, Centre Hospitalier Universitaire Lille, Lille Pasteur Institute, U1190, European Genomic Institute for Diabetes, Lille, France.
Julien PoissyDepartment of Intensive Care, Centre Hospitalier Universitaire Lille, Lille, France.
Violeta RaverdyUniversity of Lille, Inserm, Centre Hospitalier Universitaire Lille, Lille Pasteur Institute, U1190, European Genomic Institute for Diabetes, Lille, France.ORCID https://orcid.org/0000-0001-5754-2028
Jerome NouletteUniversity of Lille, Inserm, Centre Hospitalier Universitaire Lille, Lille Pasteur Institute, U1190, European Genomic Institute for Diabetes, Lille, France.
Alain DuhamelCentre Hospitalier Universitaire Lille, U2694 METRICS, University of Lille, Lille, France.
Julien LabreucheCentre Hospitalier Universitaire Lille, U2694 METRICS, University of Lille, Lille, France.
Daniel MathieuDepartment of Intensive Care, Centre Hospitalier Universitaire Lille, Lille, France.
Francois PattouUniversity of Lille, Inserm, Centre Hospitalier Universitaire Lille, Lille Pasteur Institute, U1190, European Genomic Institute for Diabetes, Lille, France.ORCID https://orcid.org/0000-0001-8388-3766
Merce JourdainDepartment of Intensive Care, Centre Hospitalier Universitaire Lille, Lille, France.ORCID https://orcid.org/0000-0001-9450-192X
LICORN and the Lille COVID-19 and Obesity study group
Inserm · FRCentre Hospitalier Universitaire de Lille · FRUniversité de Lille · FR

Funding

European Commission FEDER 12003944European Genomic Institute for Diabetes ANR-10-LABX-46Foundation Coeur et Arteres FCA R15112EE
6 · The paper itself

Abstract

objectiveThe COVID-19 pandemic is rapidly spreading worldwide, notably in Europe and North America where obesity is highly prevalent. The relation between obesity and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has not been fully documented.

methodsThis retrospective cohort study analyzed the relationship between clinical characteristics, including BMI, and the requirement for invasive mechanical ventilation (IMV) in 124 consecutive patients admitted in intensive care for SARS-CoV-2 in a single French center.

resultsObesity (BMI > 30) and severe obesity (BMI > 35) were present in 47.6% and 28.2% of cases, respectively. Overall, 85 patients (68.6%) required IMV. The proportion of patients who required IMV increased with BMI categories (P < 0.01, χ

conclusionsThe present study showed a high frequency of obesity among patients admitted in intensive care for SARS-CoV-2. Disease severity increased with BMI. Obesity is a risk factor for SARS-CoV-2 severity, requiring increased attention to preventive measures in susceptible individuals.

Indexed as

BetacoronavirusAdultAgedBody Mass IndexCoronavirus InfectionsCOVID-19FemaleFranceHospitalizationHumansMaleMiddle AgedObesityPandemicsPneumonia, ViralPrevalence

Identifiers

PMID32271993
PMCPMC7262326
OpenAlexW3016182787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.