Evidence map›Paper›PMID 32271509›Full record

SynthesisInternational braz j urol : official journal of the Brazilian Society of Urology

The association between body mass index and varicocele: A meta-analysis.

Guo Xiao-Bin, Wu Fang-Lei, Xia Hui, Yang Cheng, Cai Zhi-Xuan, Huang Zhi-Peng, Liu Cun-Dong, Guo Wen-Bin

Open access · diamondAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in International braz j urol : official journal of the Brazilian Society of Urology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Association between body mass index and varicocele among 211 989 Chinese reproductive-age males.International journal of urology : official journal of the Japanese Urological Association · 2022
    Article
  6. Article
  7. Can we recommend varicocele surgery for men with hypogonadism?International braz j urol : official journal of the Brazilian Society of Urology
    Article
  8. A decisive year to International Brazilian Journal of Urology.International braz j urol : official journal of the Brazilian Society of Urology
    Article
  9. The obesity paradox in varicocele - is the protective effect real?International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Guo Xiao-BinDepartment of Urology, The third affiliated hospital of Southern Medical University, Guangzhou, Guangdong 510630, P.R. China.
Wu Fang-LeiDepartment of Stomatology, The twelfth People's Hospital of Guangzhou, Guangzhou, Guangdong 528000, P.R. China.
Xia HuiDepartment of Urology, The third affiliated hospital of Southern Medical University, Guangzhou, Guangdong 510630, P.R. China.
Yang ChengDepartment of Urology, The third affiliated hospital of Southern Medical University, Guangzhou, Guangdong 510630, P.R. China.
Cai Zhi-XuanDepartment of Urology, The third affiliated hospital of Southern Medical University, Guangzhou, Guangdong 510630, P.R. China.
Huang Zhi-PengDepartment of Urology, The third affiliated hospital of Southern Medical University, Guangzhou, Guangdong 510630, P.R. China.
Liu Cun-DongDepartment of Urology, The third affiliated hospital of Southern Medical University, Guangzhou, Guangdong 510630, P.R. China.
Guo Wen-BinDepartment of Urology, The third affiliated hospital of Southern Medical University, Guangzhou, Guangdong 510630, P.R. China.
Third Affiliated Hospital of Southern Medical University · CNTwelfth Guangzhou City People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRecently, several studies have found that obesity had a protective effect against varicocele, but no meta-analysis has confirmed this finding. Therefore, we conducted this meta-analysis to investigate the association between body mass index (BMI) and varicocele. MATERIAL AND

methodsWe searched for studies in PubMed, Science Direct and the Cochrane Library from inception until February 2018. The association between BMI and varicocele was assessed by pooling the odds ratios (ORs).

resultsEleven eligible studies with a total study population of 1.376.658 participants were included in our analysis. According to BMI, the subjects were defined as belonging to the obese, overweight and underweight groups. Our results showed that the obese group had a lower risk of varicocele when compared with the normal weight group (odds ratio [OR] 0.46, 95% confidence intervals [CIs] 0.37-0.58). Additionally, an overweight BMI had a protective effect against varicocele (OR 0.70, 95% CIs, 0.56-0.86). However, underweight patients had a more than 30% higher risk of varicocele (OR 1.31, 95% CI, 1.04-1.64). Furthermore, there was no publication bias in any of the analyses.

conclusionsOur study demonstrates that BMI is negatively associated with the presence of varicocele.

Indexed as

VaricoceleBody Mass IndexHumansMaleObesityOdds RatioOverweightBody Mass IndexMeta-Analysis [Publication Type]Varicocele

Identifiers

PMID32271509
PMCPMC7712683
OpenAlexW3022524726

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.