Observational studyBioscience reports2020
Preoperative red cell distribution width predicts postoperative cognitive dysfunction after coronary artery bypass grafting.
Observational study in Bioscience reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 26 citations in OpenAlex.
- Morin improves postoperative cognitive dysfunction by mediating the miR-138-5p/SIRT1 axis to regulate ferroptosis.Scientific reports · 2026Article
- Association between the peak red blood cell distribution width and in-hospital mortality after post-cardiotomy extracorporeal membrane oxygenation.Journal of cardiothoracic surgery · 2025Article
- Association between estimated glomerular filtration rate and memory function mediated by brain Gray matter volumes: a cross-sectional study using the ADNI database.BMC geriatrics · 2025Article
- Effect of cognitive behavioral intervention on physical symptoms, B-type natriuretic peptide, red cell distribution width, C-reactive protein in elderly heart failure patients.Journal of cardiothoracic surgery · 2025Article
- Association between hemoglobin-to-red blood cell distribution width ratio and cognitive function in older US adults: a cross-sectional study based on the NHANES 2011-2014.Frontiers in aging neuroscience · 2025Article
- Postoperative cognitive dysfunction-current research progress.Frontiers in behavioral neuroscience · 2024Review
- Increased MCHC*RDW-SD interaction values: indicators of neurological impairment in lead-poisoned children.PeerJ · 2024Article
- Ratio of hemoglobin to red cell distribution width: an inflammatory predictor of survival in AIDS-related DLBCL.Frontiers in immunology · 2024Article
- Incidence and Factors Related to Prolonged Postoperative Cognitive Decline (POCD) in Elderly Patients Following Surgery and Anaesthesia: A Systematic Review.Journal of multidisciplinary healthcare · 2023Review
- Anesthesia and surgery-induced elevation of CSF sTREM2 is associated with early cognitive dysfunction after thoracoabdominal aortic dissection surgery.BMC anesthesiology · 2022Article
- Red blood cell distribution width predicts gastrointestinal bleeding after coronary artery bypass grafting.BMC cardiovascular disorders · 2022Observational
- Postoperative red blood cell distribution width predicts functional outcome in aneurysmal subarachnoid hemorrhage after surgical clipping: A single-center retrospective study.Frontiers in neurology · 2022Article
- The interaction and pathogenesis between cognitive impairment and common cardiovascular diseases in the elderly.Therapeutic advances in chronic disease · 2022Review
- A nomogram incorporating red blood cell indices to predict post-stroke cognitive impairment in the intracerebral hemorrhage population.Frontiers in aging neuroscience · 2022Article
- Red cell distribution width, anemia and their associations with white matter integrity among middle-aged urban adults.Neurobiology of aging · 2021Article
- Red Cell Distribution Width, Anemia, and Brain Volumetric Outcomes Among Middle-Aged Adults.Journal of Alzheimer's disease : JAD · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We assessed the relationship between red blodd cell distribution width (RDW) and postoperative cognitive dysfunction (POCD) after coronary artery bypass grafting (CABG) in patients who usually had obvious hemodynamic changes. We enrolled 362 coronary heart disease patients who received CABG. POCD was assessed through neuropsychological examination at 21 days after operation. Demographics, history of diseases, blood biochemical parameters and perioperative data were collected. The receiver operating characteristic (ROC) curve was used to find the best cut-off value of RDW for diagnosis of POCD. Logistic regression was used to explore the relationship between RDW and POCD. The 21-day incidence of POCD in patients receiving CABG was 27.1% (98/362). The RDW of POCD patients was significantly higher than in the non-POCD patients (17.4 vs. 13.2). The sensitivity and specificity of RDW for predicting POCD were 82.7 and 64.8%, respectively. The POCD patients also tended to be older and had higher fasting plasma glucose, hypersensitive c-reactive protein, tumor necrosis factor-α, white blood cell levels and longer surgery time. No significant differences were found in other parameters. The 21-day neuropsychological test results were better in the POCD patients than the non-POCD patients. After adjustment of potential factors, the preoperative high RDW was still associated with an increased risk of POCD (odds ratio (OR) = 2.52, 95% confidence interval (CI): 1.28-4.31). Our study indicates that preoperative RDW is significantly elevated in POCD patients receiving CABG. The elevated preoperative RDW is associated with an increased risk of POCD and preoperative RDW can be an independent predictor of POCD.
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