Evidence map›Paper›PMID 32271180›Full record

ReviewExercise and sport sciences reviews2020

Plasma Lactate as a Marker for Metabolic Health.

Nicholas T Broskey, Kai Zou, G Lynis Dohm, Joseph A Houmard

Open access · greenAbstract readReview
In one paragraph

Review in Exercise and sport sciences reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Lactate Metabolism and Protein Lactylation in Diabetic Kidney Disease: A Narrative Review.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Lactate Metabolism in Health and Disease.Advances in experimental medicine and biology · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Observational
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Nicholas T Broskey
Kai ZouDepartment of Exercise and Health Sciences, University of Massachusetts Boston, Boston, MA.
G Lynis Dohm
Joseph A Houmard
East Carolina University · USUniversity of Massachusetts Boston · US

Funding

LIPID METABOLISM IN OBESITY, WEIGHT LOSS AND EXERCISER01DK056112 · NIDDK · EAST CAROLINA UNIVERSITY · PI HOUMARD, JOSEPH A · 2000 to 2016
$4.5M
Metabolic inflexibility is related to elevated muscle anaerobic glycolysisR01DK120296 · NIDDK · EAST CAROLINA UNIVERSITY · PI BROSKEY, NICHOLAS, HOUMARD, JOSEPH A · 2019 to 2023
$2.6M
NIDDK NIH HHS R01 DK056112NIDDK NIH HHS R01 DK120296
6 · The paper itself

Abstract

Blood lactate concentrations traditionally have been used as an index of exercise intensity or clinical hyperlactatemia. However, more recent data suggest that fasting plasma lactate can also be indicative of the risk for subsequent metabolic disease. The hypothesis presented is that fasting blood lactate accumulation reflects impaired mitochondrial substrate use, which in turn influences metabolic disease risk.

Indexed as

BiomarkersCitric Acid CycleDiabetes Mellitus, Type 2FastingHumansLactic AcidMetabolic SyndromeMitochondria, MuscleMuscle, SkeletalObesityRisk FactorsBiomarkersLactic Acid

Identifiers

PMID32271180
PMCPMC7311283
OpenAlexW3016067733

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.