Evidence map›Paper›PMID 32270775›Full record

ArticleSaudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association

EncephalApp Stroop App predicts poor sleep quality in patients with minimal hepatic encephalopathy due to hepatitis B-induced liver cirrhosis.

Ming Luo, Xiao-Bing Yu, Sheng-Juan Hu, Fei-Hu Bai

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Integrating smart phone applications in the management of cirrhotic patients: A scoping review.JGH open : an open access journal of gastroenterology and hepatology · 2023
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Minimal hepatic encephalopathy and sleep disorders in patients with cirrhosis: Which comes first?Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ming LuoDepartment of Gastroenterology, Ningxia People's Hospital, 301 Zhengyuan North Street, Jinfeng District, Yinchuan, Ningxia, PR China.
Xiao-Bing YuDepartment of Gastroenterology, Ningxia People's Hospital, 301 Zhengyuan North Street, Jinfeng District, Yinchuan, Ningxia, PR China.
Sheng-Juan HuDepartment of Gastroenterology, Ningxia People's Hospital, 301 Zhengyuan North Street, Jinfeng District, Yinchuan, Ningxia, PR China.
Fei-Hu BaiDepartment of Gastroenterology, Ningxia People's Hospital, 301 Zhengyuan North Street, Jinfeng District, Yinchuan, Ningxia, PR China.
Ningxia Hui Autonomous Region Peoples Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimA novel computerised Stroop test- EncephalApp Stroop App (EncephalApp) has good diagnostic validity for minimal hepatic encephalopathy (MHE) in cirrhotic patients. The Stroop test is correlated with sleep disturbances which are common, and severely affects health-related quality of life in cirrhotic patients with MHE. We evaluated the relationship between sleep quality and EncephalApp results in patients with MHE due to hepatitis B-induced liver cirrhosis. PATIENTS AND

methodsWe enrolled 180 adult patients with hepatitis B-induced cirrhosis. All patients were tested using the psychometric hepatic encephalopathy score (PHES) and EncephalApp. We analysed the diagnostic validity of EncephalApp for MHE using PHES as the gold standard for reference. The sleep quality of included patients was evaluated using the Pittsburgh Sleep Quality Index (PSQI). The predictive factors for poor sleep quality were analysed using backwards conditional stepwise logistic regression analysis.

resultsNinety-eight patients (54.4%) were diagnosed with MHE by PHES. Receiver operating characteristic (ROC) curve analysis showed that the threshold value of EncephalApp for MHE diagnosis was 225.60 s. EncephalApp showed 85.2% sensitivity and 77.3% specificity for diagnosing MHE; the area under the ROC curve was 0.864. PSQI scores of cirrhotic patients with MHE were significantly lower than those without MHE (P < 0.05). Child Turcotte Pugh grades (Odds ratio [OR] = 2.11 [1.55-2.85], P < 0.01) and the total Off-time plus On-time of EncephalApp (OR = 4.14 [1.95-6.29], P < 0.01) were independent predictors of poor sleep quality in MHE patients.

conclusionsThe total Off-time plus On-time of EncephalApp predicts poor sleep quality in patients with MHE due to hepatitis B-induced cirrhosis.

Indexed as

Hepatic EncephalopathyHepatitis BLiver CirrhosisSleep Wake DisordersHumansPsychometricsQuality of LifeROC CurveEncephalApp Stroop Appminimal hepatic encephalopathysleep qualityStroop test

Identifiers

PMID32270775
PMCPMC7392289
OpenAlexW3015569188

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.