Evidence map›Paper›PMID 32270424›Full record

ArticleSleep & breathing = Schlaf & Atmung2021

Obstructive sleep apnea during rapid eye movement sleep in patients after percutaneous coronary intervention: a multicenter study.

Aye-Thandar Aung, William Kristanto, Megan Jia-Ing Tan, Chieh-Yang Koo, Pei-Qing Xu, Calvin W Chin, Glenn Roldan, As Tar Thant, Siew-Pang Chan, Ai-Ping Chua and 3 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. REM sleep obstructive sleep apnoea.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Aye-Thandar AungDepartment of Cardiology, National University Heart Centre Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 9, Singapore, 119228, Singapore.
William KristantoDepartment of Medicine, Division of Cardiology, Ng Teng Fong General Hospital, Jurong, Singapore.
Megan Jia-Ing TanDepartment of Cardiology, National University Heart Centre Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 9, Singapore, 119228, Singapore.
Chieh-Yang KooDepartment of Cardiology, National University Heart Centre Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 9, Singapore, 119228, Singapore.
Pei-Qing XuDepartment of Cardiology, National University Heart Centre Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 9, Singapore, 119228, Singapore.
Calvin W ChinDepartment of Cardiology, National Heart Centre Singapore, Singapore, Singapore.
Glenn RoldanNeuroSleep Center of the Philippines, Manila, Philippines.
As Tar ThantYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Siew-Pang ChanYong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Ai-Ping ChuaDepartment of Medicine, Division of Respiratory Medicine, Ng Teng Fong General Hospital, Jurong, Singapore.
Ferran BarbeRespiratory Department, Lleida, Catalonia and Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain.
Pipin KojodjojoDepartment of Cardiology, National University Heart Centre Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 9, Singapore, 119228, Singapore.
Chi-Hang LeeDepartment of Cardiology, National University Heart Centre Singapore, 1E Kent Ridge Road, NUHS Tower Block Level 9, Singapore, 119228, Singapore. mdclchr@nus.edu.sg.
National University Heart Centre Singapore · SGNational University of Singapore · SGNg Teng Fong General Hospital · SGCentro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESNational Heart Centre Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeObstructive sleep apnea (OSA) during the rapid eye movement (REM) stage of the sleep cycle is associated with intense hypoxemia and cardiovascular instability. We characterized OSA during REM sleep in patients after percutaneous coronary intervention.

methodsIn this multicenter study, 204 patients who had undergone percutaneous coronary intervention in the prior 6 to 36 months were recruited for in-laboratory polysomnography. The primary measure was respiratory events during REM sleep. The patients were divided into 2 groups: (1) OSA during REM sleep (≥ 15 events/h) and (2) absence of OSA during REM sleep (< 15 events/h).

resultsBased on the overall apnea-hypopnea index ≥ 15, 148 patients (74.0%) had OSA. After excluding patients with failed polysomnography or REM sleep < 30 min, 163 patients formed the cohort for this analysis. OSA during REM sleep was diagnosed in 132 patients (81%). Compared with the patients without OSA during REM sleep, those with OSA during REM sleep had a higher body mass index (p = 0.003) and systolic blood pressure (p = 0.041), and a higher prevalence of diabetes mellitus (p = 0.029). Logistic regression analysis, including age, sex, diabetes mellitus, indication for percutaneous coronary intervention, and indication for multi-vessel percutaneous coronary intervention, showed that diabetes mellitus was the only independent predictor of OSA during REM sleep (odds ratio 2.83; 95% CI, 1.17 to 6.83; p = 0.021).

conclusionIn patients treated with percutaneous coronary intervention, there was a high prevalence of OSA during REM sleep. Diabetes mellitus was an independent predictor of OSA during REM sleep.

Indexed as

Diabetes MellitusPercutaneous Coronary InterventionAcute Coronary SyndromeAgedAngina, StableBlood PressureBody Mass IndexComorbidityFemaleHumansMaleMiddle AgedMyocardial IschemiaPolysomnographySleep Apnea, ObstructiveSleep, REMCoronary stentingHypoxemiaPolysomnographySleep apnea

Identifiers

PMID32270424
OpenAlexW3016136120

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.