Evidence map›Paper›PMID 32270308›Full record

ArticleJA clinical reports2020

Anaphylaxis caused by butylscopolamine bromide: a case report.

Toshie Shiraishi, Mitsuyo Nakamura, Tatsuo Horiuchi, Tomonori Takazawa

Open access · goldAbstract read
In one paragraph

Article in JA clinical reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Toshie ShiraishiDepartment of Anesthesia, Minimally Invasive Surgery Center, Yotsuya Medical Cube, 7-7 Niban-cho, Chiyoda-ku, Tokyo, 102-0084, Japan.
Mitsuyo NakamuraDepartment of Anesthesia, Minimally Invasive Surgery Center, Yotsuya Medical Cube, 7-7 Niban-cho, Chiyoda-ku, Tokyo, 102-0084, Japan.
Tatsuo HoriuchiDepartment of Anesthesiology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan.
Tomonori TakazawaIntensive Care Unit, Gunma University Hospital, 3-39-15 Showa-machi, Maebashi, Gunma, 371-8511, Japan. takazawt@gunma-u.ac.jp.
Yotsuya Medical Cube · JPGunma University · JPGunma University Hospital · JP

Funding

Japan Society for the Promotion of Science 18K08809
6 · The paper itself

Abstract

backgroundThere have been only few reports on butylscopolamine-induced anaphylaxis despite its global usage as an anticholinergic agent for approximately 70 years. We present a case of anaphylaxis caused by butylscopolamine. CASE PRESENTATION: A 63-year-old woman underwent gastrointestinal endoscopic examination. She developed facial cyanosis and hypoxia after intravenous administration of butylscopolamine 10 mg, and her blood pressure was unmeasurable. Her hemodynamic condition recovered after a total of 0.6 mg adrenaline and bolus administration of 100 mg hydrocortisone. One hour after the onset of hypotension, both plasma histamine and serum tryptase were remarkably elevated to 271.7 nmol/L and 174 μg/L, respectively. Skin tests performed 47 days after anaphylaxis showed a positive result only for butylscopolamine among the exposed agents, which was confirmed by basophil activation tests using CD203c and CD63 as markers.

conclusionButylscopolamine has the potential to cause severe anaphylaxis; hence, identification of the causative agent is important to prevent recurrence of anaphylaxis.

Indexed as

AnaphylaxisButylscopolamineskin test

Identifiers

PMID32270308
PMCPMC7142184
OpenAlexW3015356394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.