ArticleEuropean journal of applied physiology2020
Cardio-respiratory, oxidative stress and acute mountain sickness responses to normobaric and hypobaric hypoxia in prematurely born adults.
Article in European journal of applied physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02780908 (Cardio-respiratory Responses During Hypoxic Exercise in Individuals Born Prematurely), which is not on this map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cardio-respiratory Responses During Hypoxic Exercise in Individuals Born Prematurely
Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Effectiveness of voluntary isocapnic hyperpnoea for mitigating hypoxemia and acute mountain sickness in normobaric hypoxia: a randomized crossover pilot trial.Scientific reports · 2026Trial
- Alterations in acid-base balance and high-intensity exercise performance after short-term and long-term exposure to acute normobaric hypoxic conditions.Scientific reports · 2020Trial
- A comparison of normobaric and hypobaric hypoxia effects on cerebrovascular response pre and post maximal exercise.Experimental physiology · 2026Article
- Altitude hypoxia and hypoxemia: pathogenesis and management.Signal transduction and targeted therapy · 2026Review
- Intelligent monitoring and individualized strategies for preventing altitude sickness during altitude training.Frontiers in physiology · 2025Review
- Respiratory responses to hypoxia during rest and exercise in individuals born pre-term: a state-of-the-art review.European journal of applied physiology · 2022Review
- Oxidative Stress and Diseases Associated with High-Altitude Exposure.Antioxidants (Basel, Switzerland) · 2022Review
- Similar Supine Heart Rate Variability Changes During 24-h Exposure to Normobaric vs. Hypobaric Hypoxia.Frontiers in neuroscience · 2021Article
- Irisin Is Correlated with Blood Pressure in Obstructive Sleep Apnea Patients.International journal of hypertension · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 4 countries.
Funding
Abstract
purposeWe compared the effects of hypobaric and normobaric hypoxia on select cardio-respiratory responses, oxidative stress and acute mountain sickness (AMS) severity in prematurely born individuals, known to exhibit blunted hypoxic ventilatory response.
methodsSixteen prematurely born but otherwise healthy males underwent two 8-h hypoxic exposures under: (1) hypobaric hypoxic [HH; terrestrial altitude 3840 m; P
resultsHH resulted in significantly lower resting (P = 0.010) and exercise (P = 0.004) SpO
conclusionThese data suggest that, in prematurely born adults, 8-h exposure to hypobaric, as opposed to normobaric hypoxia, provokes greater reductions in systemic oxygenation and antioxidant capacity. Further studies investigating prolonged hypobaric exposures in this population are warranted. REGISTRATION: NCT02780908 (ClinicalTrials.gov).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.