Evidence map›Paper›PMID 32270035›Full record

ArticleScience advances2020

The unconventional biogenesis of Kv7.1-KCNE1 complexes.

Anna Oliveras, Clara Serrano-Novillo, Cristina Moreno, Alicia de la Cruz, Carmen Valenzuela, Christian Soeller, Núria Comes, Antonio Felipe

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
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  4. Integrative analysis of KCNQ1 variants reveals molecular mechanisms of type 1 long QT syndrome pathogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Anna OliverasMolecular Physiology Laboratory, Departamento de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Spain.ORCID 0000-0002-5880-5245
Clara Serrano-NovilloMolecular Physiology Laboratory, Departamento de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Spain.ORCID 0000-0002-0737-7439
Cristina MorenoNational Institute of Neurological Disorders and Stroke (NIH), Bethesda, MD, USA.
Alicia de la CruzInstituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain.ORCID 0000-0002-0349-4881
Carmen ValenzuelaInstituto de Investigaciones Biomédicas Alberto Sols CSIC-UAM, Madrid, Spain.ORCID 0000-0003-3929-1960
Christian SoellerLiving Systems Institute and Biomedical Physics, University of Exeter, Exeter, UK.ORCID 0000-0002-9302-2203
Núria ComesDepartamento De Biomedicina, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.
Antonio FelipeMolecular Physiology Laboratory, Departamento de Bioquímica i Biomedicina Molecular, Institut de Biomedicina (IBUB), Universitat de Barcelona, Barcelona, Spain.ORCID 0000-0002-7294-6431
Universitat de Barcelona · ESConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESInstituto de Investigaciones Biomédicas Sols-Morreale · ESInstituto de Salud Carlos III · ESNational Institute of Neurological Disorders and Stroke · USUniversity of Exeter · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The potassium channel Kv7.1 associates with the KCNE1 regulatory subunit to trigger cardiac

Indexed as

Biological TransportBiomarkersFluorescent Antibody TechniqueGenes, ReporterHumansIon Channel GatingKCNQ1 Potassium ChannelMultiprotein ComplexesMyocytes, CardiacPotassium Channels, Voltage-GatedProtein BindingBiomarkersKCNQ1 Potassium ChannelMultiprotein ComplexesPotassium Channels, Voltage-Gated

Identifiers

PMID32270035
PMCPMC7112945
OpenAlexW3014939895

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.