ArticleScience advances2020
Inhibition of protective immunity against
Open access · goldAbstract read
In one paragraph
Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 24 citations in OpenAlex.
- Conserved CD4Nature microbiology · 2026Article
- Monoclonal antibody neutralizesInfection and immunity · 2025Article
- Article
- Rational Design and Immunological Mechanisms of Circular RNA-Based Vaccines: Emerging Frontiers in Combating Pathogen Infection.Vaccines · 2025Review
- Astrocyte-derived complement C3 facilitated microglial phagocytosis of synapses in Staphylococcus aureus-associated neurocognitive deficits.PLoS pathogens · 2025Article
- Tissue niche influences immune and metabolic profiles to Staphylococcus aureus biofilm infection.Nature communications · 2024Article
- Immunoinformatic prediction to identifyVeterinary world · 2024Article
- Immunoglobulin G subclasses confer protection againstProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Toxin expression during Staphylococcus aureus infection imprints host immunity to inhibit vaccine efficacy.NPJ vaccines · 2023Article
- A simple and efficient fluorescent labeling method inFrontiers in microbiology · 2023Article
- Current Promising Strategies against Antibiotic-Resistant Bacterial Infections.Antibiotics (Basel, Switzerland) · 2022Review
- Integrating complex host-pathogen immune environments into S. aureus vaccine studies.Cell chemical biology · 2022Review
- Antibiotic Treatment of Staphylococcus aureus Infection Inhibits the Development of Protective Immunity.Antimicrobial agents and chemotherapy · 2022Article
- Impaired T-Lymphocyte Responses During Childhood Staphylococcus aureus Infection.The Journal of infectious diseases · 2022Observational
- Tissue specificity drives protective immunity againstFrontiers in immunology · 2022Article
- Antibody-Mediated Protection against Staphylococcus aureus Dermonecrosis: Synergy of Toxin Neutralization and Neutrophil Recruitment.The Journal of investigative dermatology · 2021Article
- Virulence Factors in Coagulase-Negative Staphylococci.Pathogens (Basel, Switzerland) · 2021Review
- Evasion of Immunological Memory byFrontiers in immunology · 2021Review
- Toward an effective Staphylococcus vaccine: why have candidates failed and what is the next step?Expert review of vaccinesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Youhui SiDepartment of Surgery, University of Chicago, Chicago, IL, USA.ORCID 0000-0001-8909-221X
Fan ZhaoDepartment of Surgery, University of Chicago, Chicago, IL, USA.
Pavani BeesettyCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Daniela WeiskopfDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA.ORCID 0000-0003-2968-7371
Zhaotao LiCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.
Qiaomu TianDepartment of Surgery, University of Chicago, Chicago, IL, USA.ORCID 0000-0003-4267-7362
Maria-Luisa AlegreDepartment of Medicine, University of Chicago, Chicago, IL, USA.ORCID 0000-0001-5707-6194
Alessandro SetteDivision of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA.ORCID 0000-0001-7013-2250
Anita S ChongDepartment of Surgery, University of Chicago, Chicago, IL, USA.ORCID 0000-0003-0460-0196
Christopher P MontgomeryCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA.ORCID 0000-0001-7247-0683
University of Chicago · USNationwide Children's Hospital · USLa Jolla Institute for Immunology · US
Funding
Impact of Microbiota on Alloimmune Responses in TransplantationR01AI115716 · NIAID · UNIVERSITY OF CHICAGO · PI ALEGRE, MARIA-LUISA · 2015 to 2024
$4.3MSupramolecular nanofiber vaccinesR01AI118182 · NIAID · UNIVERSITY OF CHICAGO · PI CHONG, ANITA S, COLLIER, JOEL H · 2015 to 2019
$3.1MThe microbiota and allograft rejection: novel investigations into the consequences of obesityU01AI132898 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI ALEGRE, MARIA-LUISA, PERKINS, DAVID LINN · 2017 to 2021
$2.3MOvercoming pathogen-mediated immune evasion: a translational approach to pediatric Staphylococcus aureus vaccine development - Resubmission 01R01AI125489 · NIAID · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI MONTGOMERY, CHRISTOPHER · 2017 to 2020
$1.5MEpidemic CA-MRSA: Molecular Epidemiology and ImmunologyR01AR059414 · NIAMS · UNIVERSITY OF CHICAGO · PI ALEGRE, MARIA-LUISA, DAUM, ROBERT S. · 2010 to 2013
$1.3MPathophysiology of Staphylococcus aureaus Necrotizing Pneumonia and Severe SepsisK08AI076596 · NIAID · UNIVERSITY OF CHICAGO · PI MONTGOMERY, CHRISTOPHER · 2009 to 2013
$629kNIAID NIH HHS HHSN272201200010CNIAID NIH HHS K08 AI076596NIAID NIH HHS R01 AI115716NIAID NIH HHS R01 AI118182NIAID NIH HHS R01 AI125489NIAID NIH HHS U01 AI132898NIAMS NIH HHS R01 AR059414
Abstract
Recurrent
Indexed as
Immune ToleranceAnimalsDisease Models, AnimalExotoxinsH-2 AntigensHost-Pathogen InteractionsImmunodominant EpitopesMajor Histocompatibility ComplexMiceProtein BindingStaphylococcal InfectionsStaphylococcus aureusT-LymphocytesVaccinationExotoxinsH-2 AntigensImmunodominant Epitopesleukotoxin
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.