Evidence map›Paper›PMID 32269989›Full record

ArticleFrontiers in bioengineering and biotechnology2020

3D Printing of Bone Grafts for Cleft Alveolar Osteoplasty -

Paula Korn, Tilman Ahlfeld, Franziska Lahmeyer, David Kilian, Philipp Sembdner, Ralph Stelzer, Winnie Pradel, Adrian Franke, Martina Rauner, Ursula Range and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Stem Cell-Based Tissue Engineering for Cleft Defects: Systematic Review and Meta-Analysis.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2024
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  18. Micro-porous PLGA/Regenerative biomaterials · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Paula KornDepartment of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
Tilman AhlfeldCentre for Translational Bone, Joint and Soft Tissue Research, University Hospital "Carl Gustav Carus", Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.
Franziska LahmeyerDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine "Carl Gustav Carus", Technische Universität Dresden, Dresden, Germany.
David KilianCentre for Translational Bone, Joint and Soft Tissue Research, University Hospital "Carl Gustav Carus", Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.
Philipp SembdnerInstitute of Machine Elements and Machine Design, Technische Universität Dresden, Dresden, Germany.
Ralph StelzerInstitute of Machine Elements and Machine Design, Technische Universität Dresden, Dresden, Germany.
Winnie PradelDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine "Carl Gustav Carus", Technische Universität Dresden, Dresden, Germany.
Adrian FrankeDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine "Carl Gustav Carus", Technische Universität Dresden, Dresden, Germany.
Martina RaunerDivision of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III and Center for Healthy Aging, Faculty of Medicine "Carl Gustav Carus", Technische Universität Dresden, Dresden, Germany.
Ursula RangeInstitute for Medical Informatics and Biometry, Faculty of Medicine "Carl Gustav Carus", Technische Universität Dresden, Dresden, Germany.
Bernd StadlingerClinic of Cranio-Maxillofacial and Oral Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
Anja LodeCentre for Translational Bone, Joint and Soft Tissue Research, University Hospital "Carl Gustav Carus", Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.
Günter LauerDepartment of Oral and Maxillofacial Surgery, Faculty of Medicine "Carl Gustav Carus", Technische Universität Dresden, Dresden, Germany.
Michael GelinskyCentre for Translational Bone, Joint and Soft Tissue Research, University Hospital "Carl Gustav Carus", Faculty of Medicine, Technische Universität Dresden, Dresden, Germany.
TU Dresden · DEUniversity Hospital Carl Gustav Carus · DEHumboldt-Universität zu Berlin · DEUniversity Hospital of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the most common hereditary craniofacial anomalies in humans are cleft lip and cleft alveolar bone with or without cleft palate. Current clinical practice, the augmentation of the persisting alveolar bone defect by using autologous bone grafts, has considerable disadvantages motivating to an intensive search for alternatives. We developed a novel therapy concept based on 3D printing of biodegradable calcium phosphate-based materials and integration of osteogenic cells allowing fabrication of patient-specific, tissue-engineered bone grafts. Objective of the present study was the

Indexed as

3D printingalveolar cleft modelbone graftbone tissue engineeringcalcium phosphate cement

Identifiers

PMID32269989
PMCPMC7109264
OpenAlexW3013152097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.