Evidence map›Paper›PMID 32269968›Full record

ReviewFrontiers in cellular and infection microbiology2020

Memory and Memory-Like NK Cell Responses to Microbial Pathogens.

Marc Brillantes, Aimee M Beaulieu

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 65 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Differential impact of TIM-3 ligands on NK cell function.Journal for immunotherapy of cancer · 2025
    Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Marc BrillantesCenter for Immunity and Inflammation, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers-The State University of New Jersey, Newark, NJ, United States.
Aimee M BeaulieuCenter for Immunity and Inflammation, New Jersey Medical School, Rutgers Biomedical and Health Sciences, Rutgers-The State University of New Jersey, Newark, NJ, United States.
Rutgers HealthRutgers, The State University of New Jersey · US

Funding

Innate Immune Mechanisms at the Maternal-Fetal Interface in Normal and Superovulatory PregnancyR01AI148695 · NIAID · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI BEAULIEU, AIMEE MELISSA, DOUGLAS, NATAKI C · 2019 to 2023
$3.8M
Birc5 as a regulator of NK cell development and immune functionR01HL139818 · NHLBI · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI BEAULIEU, AIMEE MELISSA · 2019 to 2023
$1.9M
Regulation of innate lymphocyte function by Zbtb32K22AI116802 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI BEAULIEU, AIMEE MELISSA · 2016 to 2017
$270k
NHLBI NIH HHS R01 HL139818NIAID NIH HHS K22 AI116802NIAID NIH HHS R01 AI148695
6 · The paper itself

Abstract

NK cells are cytotoxic lymphocytes that provide systemic defense against pathogens and malignancy. Although historically considered cells of the innate immune system, NK cells are now known to be capable of memory or memory-like immune responses in certain settings. Memory NK responses were initially reported over a decade ago in studies involving mouse models of cytomegalovirus infection and delayed-type hypersensitivity reactions to chemical haptens and viral antigens. Since then, a growing body of literature suggests that memory or memory-like NK cell responses may occur in a broader range of immunological settings, including in response to various viral and bacterial infections, and some immunization protocols. Memory-like NK cell responses have also now been reported in humans and non-human primates. Here, we summarize recent studies demonstrating memory or memory-like responses by NK cells in settings of infection and immunization against infectious agents.

Indexed as

Immunologic MemoryKiller Cells, NaturalAnimalsAntigens, ViralDisease Models, AnimalPrimatesAntigens, Viraladaptive NK cellsinfectionmemory-like NK cellsmemory NK cellsnatural killer cells

Identifiers

PMID32269968
PMCPMC7109401
OpenAlexW3013045668

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.