Evidence map›Paper›PMID 32269844›Full record

ArticleJournal of gastric cancer2020

Multicenter Retrospective Analysis of Intraperitoneal Paclitaxel and Systemic Chemotherapy for Advanced Gastric Cancer with Peritoneal Metastasis.

Dong-Wook Kim, Ye Seob Jee, Chang Hyun Kim, Jin-Jo Kim, Sungsoo Park, Sung Il Choi, Joong-Min Park, Jong-Han Kim, PIPS-GC (Perioperative Intra-Peritoneal & Systemic Chemotherapy for Gastric Cancer) study group

Open access · hybridAbstract read
In one paragraph

Article in Journal of gastric cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Asian consensus on normothermic intraperitoneal and systemic treatment for gastric cancer with peritoneal metastasis.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2025
    Article
  5. Article
  6. Article
  7. Integration of Genomic Biology Into Therapeutic Strategies of Gastric Cancer Peritoneal Metastasis.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Dong-Wook KimDepartment of Surgery, Dankook University Hospital, Cheonan, Korea.ORCID https://orcid.org/0000-0002-3552-5988
Ye Seob JeeDepartment of Surgery, Dankook University Hospital, Cheonan, Korea.ORCID https://orcid.org/0000-0003-3280-6351
Chang Hyun KimDepartment of Surgery, Incheon St. Mary's Hospital, Incheon, Korea.ORCID https://orcid.org/0000-0003-1567-4318
Jin-Jo KimDepartment of Surgery, Incheon St. Mary's Hospital, Incheon, Korea.ORCID https://orcid.org/0000-0003-1011-8793
Sungsoo ParkDepartment of Surgery, Korea University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-1779-8683
Sung Il ChoiDepartment of Surgery, Kyung Hee University Hospital at Gangdong, Seoul, Korea.ORCID https://orcid.org/0000-0002-0662-0951
Joong-Min ParkDepartment of Surgery, Chung-Ang University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-8582-6391
Jong-Han KimDepartment of Surgery, Korea University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3862-8501
PIPS-GC (Perioperative Intra-Peritoneal & Systemic Chemotherapy for Gastric Cancer) study group
Korea University · KRDankook University Hospital · KRChung-Ang University · KRKyung Hee University Hospital at Gangdong · KRThe Catholic University of Korea Incheon St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe objective of the present retrospective analysis was to describe the experience of intraperitoneal (IP) paclitaxel and systemic chemotherapy in patients with peritoneal metastasis (PM) of advanced gastric cancer (AGC) in a multicenter setting in Korea. MATERIALS AND

methodsThe medical records of patients with AGC, who were diagnosed with PM between January 2015 and December 2018, were reviewed. IP catheter was placed in the pouch of Douglas and was used for the administration of IP paclitaxel chemotherapy.

resultsWe reviewed the clinical outcomes of IP paclitaxel and systemic chemotherapy administration in 82 patients at six institutions in Korea. Mean number of IP chemotherapy cycles was 6.6. The mean peritoneal cancer index (PCI) was 21.9. Postoperative complications related to IP catheter and port were observed in 15 patients. The overall median survival was 20.0 months. A significant difference was observed in the survival rate according to the ascites grade (grade I and II, 24.1 months; grade III and IV, 15.3 months; P=0.014) and PCI grade (grade I, 25.6 months; grade II and III, 16.3 months; P=0.023).

conclusionsThe feasibility of IP paclitaxel and systemic chemotherapy administration was demonstrated in this experience-based retrospective analysis suggesting that the procedure is beneficial in patients with PM of AGC.

Indexed as

Advanced gastric cancerIntraperitoneal chemotherapyPeritoneal metastasis

Identifiers

PMID32269844
PMCPMC7105410
OpenAlexW3008751939

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.