Evidence map›Paper›PMID 32269772›Full record

ArticleMultidisciplinary respiratory medicine2020

Fractional Exhaled Nitric Oxide (FENO) in the management of asthma: a position paper of the Italian Respiratory Society (SIP/IRS) and Italian Society of Allergy, Asthma and Clinical Immunology (SIAAIC).

Enrico Heffler, Giovanna Elisiana Carpagnano, Elisabetta Favero, Giuseppe Guida, Mauro Maniscalco, Andrea Motta, Giovanni Paoletti, Giovanni Rolla, Eugenio Baraldi, Vincenza Pezzella and 2 more

Abstract read
In one paragraph

Article in Multidisciplinary respiratory medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  12. Highly Efficient UV-Activated TiOACS applied materials & interfaces · 2025
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  16. Airways Type-2 Related Disorders: Multiorgan, Systemic or Syndemic Disease?International journal of molecular sciences · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Enrico HefflerPersonalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center IRCCS, Rozzano (MI).
Giovanna Elisiana CarpagnanoDepartment of Medical and Surgical Sciences, University of Foggia; Section of Respiratory Diseases, Hospital d'Avanzo, Foggia.
Elisabetta FaveroDepartment of Medicine-DIMED, Immunological and Respiratory Rare Disease, Allergologic Clinic Ca' Foncello Hospital, Treviso.
Giuseppe GuidaAllergy and Pneumology Unit, A.O. S. Croce e Carle, Cuneo.
Mauro ManiscalcoRespiratory Rehabilitation Unit, ICS Maugeri, Institute of Telese Terme IRCCS.
Andrea MottaInstitute of Biomolecular Chemistry, National Research Council, Pozzuoli (NA).
Giovanni PaolettiPersonalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center IRCCS, Rozzano (MI).
Giovanni RollaAllergy and Clinical Immunology, University of Turin and A.O. Mauriziano, Turin.
Eugenio BaraldiDepartment of Woman's and Child's Health, University Hospital of Padua.
Vincenza PezzellaDepartment of Woman, Child and of General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples.
Giorgio PiacentiniPaediatric Section, Department of Surgery, Dentistry, Paediatrics and Gynaecology, University of Verona.
Stefano NardiniItalian Respiratory Society-Società Italiana di Pneumologia, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma prevalence in Italy is on the rise and is estimated to be over 6% of the general population. The diagnosis of asthma can be challenging and elusive, especially in children and the last two decades has brought evidences that asthma is not a single disease but consists of various phenotypes. Symptoms can be underestimated by the patient or underreported to the clinician and physical signs can be scanty. Usual objective measures, like spirometry, are necessary but sometimes not significant. Despite proper treatment, asthma can be a very severe condition (even leading to death), however new drugs have recently become available which can be very effective in its control. Since asthma is currently thought to be caused by inflammation, a direct measure of the latter can be of paramount importance. For this purpose, the measurement of Fractional Exhaled Nitric Oxide (FE

Indexed as

Asthma diagnosisasthma managementFractional Exhaled Nitric Oxide (FENO)

Identifiers

PMID32269772
PMCPMC7137762

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.