Evidence map›Paper›PMID 32269710›Full record

ArticleAmerican journal of translational research2020

LncRNA TUG1 regulates autophagy-mediated endothelial-mesenchymal transition of liver sinusoidal endothelial cells by sponging miR-142-3p.

Rui Zhang, Xiao-Quan Huang, Ying-Yi Jiang, Na Li, Jian Wang, Shi-Yao Chen

Open access · greenAbstract read
In one paragraph

Article in American journal of translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Deciphering the role ofWorld journal of hepatology · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. The role of autophagy in hepatic fibrosis.American journal of translational research · 2021
    Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rui ZhangDepartment of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University Shanghai, P. R. China.
Xiao-Quan HuangDepartment of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University Shanghai, P. R. China.
Ying-Yi JiangDepartment of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University Shanghai, P. R. China.
Na LiDepartment of Infectious Diseases, Zhongshan Hospital, Fudan University Shanghai, P. R. China.
Jian WangDepartment of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University Shanghai, P. R. China.
Shi-Yao ChenDepartment of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University Shanghai, P. R. China.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accumulating evidence indicates that competing endogenous RNA networks play a critical role in cirrhosis progression. However, their biological role and regulatory mechanisms in liver sinusoidal endothelial cells (LSECs) have not been explored. Here, we exposed LSECs to starvation and lipopolysaccharide (LPS) treatment and assessed changes in TUG1 and miR-142-3p expression, autophagy, and endothelial-mesenchymal transition (EndMT). We confirmed the effects of targeted binding between miR-142-3p and TUG1 or ATG5 by luciferase activity and radio-immunoprecipitation assay. Using an

Indexed as

Autophagyendothelial-mesenchymal transitionliver sinusoidal endothelial cellsmiR-142-3pTUG1

Identifiers

PMID32269710
PMCPMC7137070
OpenAlexW3028050608

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.