ArticleInternational journal of clinical and experimental pathology2020
Impact of gender on survival in patients with laryngeal squamous cell carcinoma: a propensity score matching analysis.
Article in International journal of clinical and experimental pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Association of Charlson-Deyo Comorbidity Index With Survival Following Upfront Laryngectomy for Laryngeal Squamous Cell Carcinoma.Laryngoscope investigative otolaryngology · 2026Article
- Female sex is associated with worse survival in laryngeal head and neck squamous cell carcinoma.The oncologist · 2026Article
- VEGFA (rs1570360, rs699947, rs3025033, rs2146323, rs3024997) genotypes in patients with laryngeal squamous cell carcinoma.BMC cancer · 2025Article
- Laryngeal Cancer in the Modern Era: Evolving Trends in Diagnosis, Treatment, and Survival Outcomes.Journal of clinical medicine · 2025Review
- Laryngeal Cancer in Women: Unveiling Gender-Specific Risk Factors, Treatment Challenges, and Survival Disparities.Current oncology (Toronto, Ont.) · 2024Review
- Laryngeal Cancer: Epidemiology, Etiology, and Prevention: A Narrative Review.Iranian journal of public health · 2023Review
- Downregulation of zinc finger protein 71 in laryngeal squamous cell carcinoma tissues and its potential molecular mechanism and clinical significance: a study based on immunohistochemistry staining and data mining.World journal of surgical oncology · 2022Article
- Glycolysis related gene expression signature in predicting prognosis of laryngeal squamous cell carcinoma.Bioengineered · 2021Article
- Role of Human Papilloma Virus 16/18 In Laryngeal Carcinoma with Correlation to the Expression of Cyclin D1, p53, p16 and EGFR.Pakistan journal of medical sciencesArticle
- Impact ofCancer genomics & proteomicsArticle
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn the world, there are approximately 160,000 cases of laryngeal cancer newly diagnosed every year and 95% of the cases are squamous cell carcinoma (LSCC). We conduct this study to investigate the influencing factors in LSCC.
methodWe used cohort of LSCC cases form the Surveillance, Epidemiology, and End Results (SEER) database (1973-2014) to investigate the relationship between gender and survival. We conducted 1:1 propensity matching to mimic randomized controlled trials. Using the matched group, we investigate the effect of gender on cancer-specific survival (CSS) and overall survival (OS).
resultIn total, 47881 patients were brought into an unmatched cohort and 17985 cases were brought into a matched cohort. Using the matched group, we conducted a survival analysis. The 1-year, 3-year, and 5-year CSS and OS rates were better in female patients and the subgroup analysis showed the same trend. Cox regression analysis showed gender was an independent prognostic indicator for LSCC patients.
conclusionGender is an independent prognostic indicator for LSCC patients. Male patients are a high-risk population.
Indexed as
Identifiers
32269698PMC7137017What OpenQuestion holds
Registered trials
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