Evidence map›Paper›PMID 32269565›Full record

Observational studyFrontiers in immunology2020

Molecular Fingerprints of Borderline Changes in Kidney Allografts Are Influenced by Donor Category.

Petra Hruba, Zdenek Krejcik, Michaela Dostalova Merkerova, Jiri Klema, Viktor Stranecky, Janka Slatinska, Jana Maluskova, Eva Honsova, Ondrej Viklicky

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. CCL13 and human diseases.Frontiers in immunology · 2023
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Petra HrubaTransplant Laboratory, Institute for Clinical and Experimental Medicine, Prague, Czechia.
Zdenek KrejcikDepartment of Genomics, Institute of Haematology and Blood Transfusion, Prague, Czechia.
Michaela Dostalova MerkerovaDepartment of Genomics, Institute of Haematology and Blood Transfusion, Prague, Czechia.
Jiri KlemaDepartment of Computer Science, Faculty of Electrical Engineering, Czech Technical University, Prague, Czechia.
Viktor StraneckyDepartment of Paediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University, Prague, Czechia.
Janka SlatinskaDepartment of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czechia.
Jana MaluskovaDepartment of Pathology, Institute for Clinical and Experimental Medicine, Prague, Czechia.
Eva HonsovaDepartment of Pathology, Institute for Clinical and Experimental Medicine, Prague, Czechia.
Ondrej ViklickyTransplant Laboratory, Institute for Clinical and Experimental Medicine, Prague, Czechia.
Institute of Clinical and Experimental Medicine · CZInstitute of Haematology and Blood Transfusion · CZCharles University · CZCzech Technical University in Prague · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fate of transplanted kidneys is substantially influenced by graft quality, with transplantation of kidneys from elderly and expanded criteria donors (ECDs) associated with higher occurrence of delayed graft function, rejection, and inferior long-term outcomes. However, little is known about early molecular fingerprints of these events in different donor categories. Borderline changes represent the most frequent histological finding early after kidney transplantation. Therefore, we examined outcomes and transcriptomic profiles of early-case biopsies diagnosed as borderline changes in different donor categories. In this single-center, retrospective, observational study, we compared midterm outcomes of kidney transplant recipients with early borderline changes as a first pathology between ECD (

Indexed as

AllograftsTissue DonorsTranscriptomeAdultDelayed Graft FunctionFemaleHumansKidney TransplantationMaleMiddle AgedRetrospective Studiesborderline changesgene expressionkidney transplantationmarginal donormicroarray

Identifiers

PMID32269565
PMCPMC7109293
OpenAlexW3013295531

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.