ReviewFrontiers in neurology2020
Imaging the Premonitory Phase of Migraine.
Review in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 36 citations in OpenAlex.
- The Effect of Melatonin on Reducing the Frequency and Severity of Migraine Attacks: A Double-Blind, Randomized Clinical Trial.Iranian journal of medical sciences · 2024Trial
- Clinical characteristics of perimenopausal migraine and its correlation to hormonal levels.The journal of headache and pain · 2026Article
- Triggers, prodrome, aura, and headache interactions in migraine with typical aura: a prospective deep-phenotyping study.The journal of headache and pain · 2026Observational
- Persistent postural-perceptual dizziness versus vestibular migraine: A narrative review.Headache · 2026Review
- Symptoms across the phases of the migraine cycle from the patient's perspective: Results of the MiCOAS qualitative study.Headache · 2025Article
- Migraine and Its Treatment from the Medicinal Chemistry Perspective.ACS pharmacology & translational science · 2024Review
- The premonitory phase of migraine is due to hypothalamic dysfunction: revisiting the evidence.The journal of headache and pain · 2022Review
- Migraine: interactions between brain's trait and state.CNS spectrums · 2022Review
- Exploring the neurobiology of the premonitory phase of migraine preclinically - a role for hypothalamic kappa opioid receptors?The journal of headache and pain · 2022Article
- Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine.Brain : a journal of neurology · 2022Article
- A Comprehensive Review of Zavegepant as Abortive Treatment for Migraine.Health psychology research · 2022Review
- Article
- A link between migraine and prolactin: the way forward.Future science OA · 2021Review
- Hormonal influences in migraine - interactions of oestrogen, oxytocin and CGRP.Nature reviews. Neurology · 2021Review
- Follow-Up of a Case of Dopamine-Mediated Yawning-Fatigue-Syndrome Responsive to Opioids, Successful Desensitization via Graded Activity Treatment.Neurology international · 2021Article
- Headache Medicine Grand Challenge: Headache: A New Frontier, A New Challenge.Frontiers in pain research (Lausanne, Switzerland) · 2021Article
- Migraine Is More Than Just Headache: Is the Link to Chronic Fatigue and Mood Disorders Simply Due to Shared Biological Systems?Frontiers in human neuroscience · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Migraine is a common and disabling brain disorder with a broad and heterogeneous phenotype, involving both pain and painless symptoms. Over recent years, more clinical and research attention has been focused toward the premonitory phase of the migraine attack, which can start up to days before the onset of head pain. This early phase can involve symptomatology, such as cognitive and mood change, yawning, thirst and urinary frequency and sensory sensitivities, such as photophobia and phonophobia. In some patients, these symptoms can warn of an impending headache and therefore offer novel neurobiological insights and therapeutic potential. As well as characterization of the phenotype of this phase, recent studies have attempted to image this early phase using functional neuroimaging and tried to understand how the symptoms are mediated, how a migraine attack may be initiated, and how nociception may follow thereafter. This review will summarize the recent and evolving findings in this field and hypothesize a mechanism of subcortical and diencephalic brain activation during the start of the attack, including that of basal ganglia, hypothalamus, and thalamus prior to headache, which causes a top-down effect on brainstem structures involved in trigeminovascular nociception, leading ultimately to headache.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.