Evidence map›Paper›PMID 32269315›Full record

ReviewNature reviews. Neuroscience2020

The influence of subcortical shortcuts on disordered sensory and cognitive processing.

Jessica McFadyen, Raymond J Dolan, Marta I Garrido

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Article
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  6. A Direct Auditory Subcortical Route to the Amygdala Associated with Fear in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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  7. Article
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  9. In vivo parcellation of the human superior colliculus from brain-wide probabilistic connectivity.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
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  12. [Analyzing Frequency-Dependent Human Brain Information Flow in Resting-State fMRI Using Multiple Effective Connectivity Methods].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025
    Article
  13. Visual Perceptual Processing Abnormalities in Body Dysmorphic Disorder.Current topics in behavioral neurosciences · 2025
    Review
  14. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jessica McFadyenMax Planck UCL Centre for Computational Psychiatry and Ageing Research, London, UK. j.mcfadyen@ucl.ac.uk.ORCID http://orcid.org/0000-0003-1415-2286
Raymond J DolanMax Planck UCL Centre for Computational Psychiatry and Ageing Research, London, UK.
Marta I GarridoQueensland Brain Institute, University of Queensland, Brisbane, Australia.ORCID http://orcid.org/0000-0003-0679-4959

Funding

Wellcome Trust 091593/Z/10/ZWellcome Trust 098362/A/12/Z
6 · The paper itself

Abstract

The very earliest stages of sensory processing have the potential to alter how we perceive and respond to our environment. These initial processing circuits can incorporate subcortical regions, such as the thalamus and brainstem nuclei, which mediate complex interactions with the brain's cortical processing hierarchy. These subcortical pathways, many of which we share with other animals, are not merely vestigial but appear to function as 'shortcuts' that ensure processing efficiency and preservation of vital life-preserving functions, such as harm avoidance, adaptive social interactions and efficient decision-making. Here, we propose that functional interactions between these higher-order and lower-order brain areas contribute to atypical sensory and cognitive processing that characterizes numerous neuropsychiatric disorders.

Indexed as

AnimalsBrain StemCerebral CortexCognitive DysfunctionHumansNeural PathwaysSensation DisordersThalamus

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.