ArticleScience translational medicine2020
Development of a neural interface for high-definition, long-term recording in rodents and nonhuman primates.
Article in Science translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 100 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
100 citing papers in PubMed, 214 citations in OpenAlex.
- A soft bioelectronic system with a responsive hydrogel neural interface for direct force quantification and real-time intraoperative craniocerebral injury monitoring.Nature biomedical engineering · 2026Article
- Towards maximizing optical access through Smart Dura.Journal of neural engineering · 2026Article
- Distinct neural processes link speech planning and execution.Nature human behaviour · 2026Article
- Combining phase analysis and causal stimulation enables longitudinal mesoscale connectivity mapping.bioRxiv : the preprint server for biology · 2026Article
- A Thin Film Transistor Backplane for Scalable Chronic Neural Interfaces.bioRxiv : the preprint server for biology · 2026Article
- Ion-shielding ultrathin encapsulation with hot-press bonded interface enables chronic stretchable bioelectronics.Science advances · 2026Article
- Bridging the Gap: Integrated High-Density Microelectrode Arrays for Cellular, Organoid, and Clinical Electrophysiology.Micromachines · 2026Review
- Multimodal Optical Imaging and Modulation with Simultaneous Electrophysiology Through Smart Dura in Non-Human Primates.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Transforming healthcare through in-body bioelectronic systems.Nature communications · 2026Review
- Primate neuroethology: a new synthesis.Trends in cognitive sciences · 2026Review
- Tantalum Interconnect Metallization for Thin-Film Neural Interface Devices.Micromachines · 2026Article
- Smart Dura: a functional artificial dura for multi-modal neural recording and modulation.Microsystems & nanoengineering · 2026Article
- A large-scale optogenetic neurophysiology platform for improving accessibility in non-human primate behavioral experiments.Nature communications · 2026Article
- Growth-adaptive spring electronics for long-term, same-neuron mapping in the developing rat brain.bioRxiv : the preprint server for biology · 2026Article
- Intracortical Microstimulation in Brain-Computer Interfaces: Evoking Perception and Plasticity.Cyborg and bionic systems (Washington, D.C.) · 2026Review
- An Active, Multimodal Neural Interface for Real-Time Monitoring of Cortical Electrical, Thermal, and Optical Dynamics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Distributed implantable microchips as wireless networks for neural sensing and stimulation.Frontiers in neuroscience · 2026Review
- A wireless subdural-contained brain-computer interface with 65,536 electrodes and 1,024 channels.Nature electronics · 2025Article
- Long-Term Stable Neural Interfaces with Nanoporous Graphene Electrodes and Hybrid Polyimide-Aluminium Oxide Encapsulation.Small methods · 2025Article
- Neural vs Neuromorphic Interfaces: Where Are We Standing?Chemical reviews · 2025Review
40 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 13 institutions in 3 countries.
Funding
Abstract
Long-lasting, high-resolution neural interfaces that are ultrathin and flexible are essential for precise brain mapping and high-performance neuroprosthetic systems. Scaling to sample thousands of sites across large brain regions requires integrating powered electronics to multiplex many electrodes to a few external wires. However, existing multiplexed electrode arrays rely on encapsulation strategies that have limited implant lifetimes. Here, we developed a flexible, multiplexed electrode array, called "Neural Matrix," that provides stable in vivo neural recordings in rodents and nonhuman primates. Neural Matrix lasts over a year and samples a centimeter-scale brain region using over a thousand channels. The long-lasting encapsulation (projected to last at least 6 years), scalable device design, and iterative in vivo optimization described here are essential components to overcoming current hurdles facing next-generation neural technologies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.