Evidence map›Paper›PMID 32269089›Full record

ArticleThe European respiratory journal2020

ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19.

Janice M Leung, Chen X Yang, Anthony Tam, Tawimas Shaipanich, Tillie-Louise Hackett, Gurpreet K Singhera, Delbert R Dorscheid, Don D Sin

Abstract readLetter
In one paragraph

Article in The European respiratory journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 527 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
527citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

527 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Gut distress and interventionFrontiers in public health · 2023
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Long COVID After Bamlanivimab Treatment.The Journal of infectious diseases · 2023
    Trial
  6. Trial
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Loss of Lung Function Led to Loss of Life during the COVID-19 Pandemic.American journal of respiratory and critical care medicine · 2025
    Article

467 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Janice M LeungUniversity of British Columbia (UBC) Centre for Heart Lung Innovation, Vancouver, BC, Canada.
Chen X YangUniversity of British Columbia (UBC) Centre for Heart Lung Innovation, Vancouver, BC, Canada.
Anthony TamUniversity of British Columbia (UBC) Centre for Heart Lung Innovation, Vancouver, BC, Canada.
Tawimas ShaipanichDept of Medicine (Division of Respirology), University of British Columbia, Vancouver, BC, Canada.
Tillie-Louise HackettDept of Medicine (Division of Respirology), University of British Columbia, Vancouver, BC, Canada.
Gurpreet K SingheraUniversity of British Columbia (UBC) Centre for Heart Lung Innovation, Vancouver, BC, Canada.
Delbert R DorscheidUniversity of British Columbia (UBC) Centre for Heart Lung Innovation, Vancouver, BC, Canada.
Don D SinUniversity of British Columbia (UBC) Centre for Heart Lung Innovation, Vancouver, BC, Canada don.sin@hli.ubc.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Up-RegulationAcute Lung InjuryAdultAngiotensin-Converting Enzyme 2Case-Control StudiesCohort StudiesCoronavirus InfectionsCOVID-19EpitheliumFemaleHumansLungMaleMiddle AgedPandemicsPeptidyl-Dipeptidase AACE2 protein, humanAngiotensin-Converting Enzyme 2Peptidyl-Dipeptidase A

Identifiers

PMID32269089
PMCPMC7144263

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.