Evidence map›Paper›PMID 32269068›Full record

ArticleScience (New York, N.Y.)2020

Susceptibility of ferrets, cats, dogs, and other domesticated animals to SARS-coronavirus 2.

Jianzhong Shi, Zhiyuan Wen, Gongxun Zhong, Huanliang Yang, Chong Wang, Baoying Huang, Renqiang Liu, Xijun He, Lei Shuai, Ziruo Sun and 11 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04716543 (One-health Approach in Epidemiological Investigation of SARS-CoV-2 in Laos), which is not on this map. Cited by 1,186 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1,186citing papers in PubMed, 1 pooled it
45.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04716543 unknown statusnot on this mapstarted 2021, after this paper: background citation

One-health Approach in Epidemiological Investigation of SARS-CoV-2 in Laos

TypeobservationalSponsorANRS, Emerging Infectious DiseasesRan2021 to 2022Enrolled5,400ConditionsInfluenza -Like Illness, Covid19ArmsILI and COVID-19 detection
3 · Its place in the literature

Who cites it

1,186 citing papers in PubMed, 1 synthesis or guideline pooled it, 2,021 citations in OpenAlex.

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  7. Diffuse alveolar damage, acute respiratory distress syndrome (ARDS), and non-cardiogenic pulmonary edema. Part 1: ARDS endotypes, including systemic inflammatory response syndrome and sepsis, with dog and cat examples.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2026
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1,126 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 3 institutions in 1 country.

Jianzhong Shi *State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China.ORCID 0000-0003-4580-9455
Zhiyuan Wen *State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China.ORCID 0000-0003-3112-0243
Gongxun Zhong *State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China.ORCID 0000-0002-0748-9641
Huanliang Yang *State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China.ORCID 0000-0002-2049-332X
Chong Wang *State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China.ORCID 0000-0002-3970-9071
Baoying Huang *National Institute for Viral Disease Control and Prevention, China CDC, Beijing 102206, People's Republic of China.ORCID 0000-0001-9516-1146
Renqiang LiuState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China.
Xijun HeNational High Containment Laboratory for Animal Diseases Control and Prevention, Harbin 150069, People's Republic of China.
Lei ShuaiState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China.
Ziruo SunState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China.
Yubo ZhaoState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China.
Peipei LiuNational Institute for Viral Disease Control and Prevention, China CDC, Beijing 102206, People's Republic of China.ORCID 0000-0001-8374-9823
Libin LiangState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China.
Pengfei CuiState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China.
Jinliang WangState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China.
Xianfeng ZhangNational High Containment Laboratory for Animal Diseases Control and Prevention, Harbin 150069, People's Republic of China.ORCID 0000-0001-9486-8262
Yuntao GuanNational High Containment Laboratory for Animal Diseases Control and Prevention, Harbin 150069, People's Republic of China.
Wenjie TanNational Institute for Viral Disease Control and Prevention, China CDC, Beijing 102206, People's Republic of China.ORCID 0000-0002-5963-1136
Guizhen WuNational Institute for Viral Disease Control and Prevention, China CDC, Beijing 102206, People's Republic of China. buzhigao@caas.cn chenhualan@caas.cn wugz@ivdc.chinacdc.cn.ORCID 0000-0003-2778-4290
Hualan ChenState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China. buzhigao@caas.cn chenhualan@caas.cn wugz@ivdc.chinacdc.cn.ORCID 0000-0001-8910-898X
Zhigao BuState Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin 150069, People's Republic of China. buzhigao@caas.cn chenhualan@caas.cn wugz@ivdc.chinacdc.cn.ORCID 0000-0001-9242-4211
Chinese Academy of Agricultural Sciences · CNChina Animal Disease Control Center · CNNational Institute for Viral Disease Control and Prevention · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) causes the infectious disease COVID-19 (coronavirus disease 2019), which was first reported in Wuhan, China, in December 2019. Despite extensive efforts to control the disease, COVID-19 has now spread to more than 100 countries and caused a global pandemic. SARS-CoV-2 is thought to have originated in bats; however, the intermediate animal sources of the virus are unknown. In this study, we investigated the susceptibility of ferrets and animals in close contact with humans to SARS-CoV-2. We found that SARS-CoV-2 replicates poorly in dogs, pigs, chickens, and ducks, but ferrets and cats are permissive to infection. Additionally, cats are susceptible to airborne transmission. Our study provides insights into the animal models for SARS-CoV-2 and animal management for COVID-19 control.

Indexed as

Animals, DomesticCoronavirus InfectionsDisease Models, AnimalDisease SusceptibilityFerretsPandemicsPneumonia, ViralAnimalsAntibodies, ViralBetacoronavirusCatsChickensCOVID-19DogsDucksFecesAntibodies, ViralRNA, Viral

Identifiers

PMID32269068
PMCPMC7164390
OpenAlexW3014233146

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.