Evidence map›Paper›PMID 32268921›Full record

ArticleCritical care (London, England)2020

Alveolar MMP28 is associated with clinical outcomes and measures of lung injury in acute respiratory distress syndrome.

Eric D Morrell, Carmen Mikacenic, Ke-Qin Gong, Susanna Kosamo, Mark M Wurfel, Anne M Manicone

Open access · goldAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Critical care (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Role of the extracellular matrix in COVID-19.World journal of clinical cases · 2023
    Review
  2. Possible Role of Matrix Metalloproteinases and TGF-β in COVID-19 Severity and Sequelae.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2022
    Review
  3. The Lung Elastin Matrix Undergoes Rapid Degradation Upon Adult Loss ofFrontiers in cell and developmental biology · 2021
    Article
  4. Alveolar CCN1 is associated with mechanical stretch and acute respiratory distress syndrome severity.American journal of physiology. Lung cellular and molecular physiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Eric D MorrellDivision of Pulmonary, Critical Care, and Sleep Medicine, Center for Lung Biology, University of Washington, 850 Republican St, Seattle, WA, 98109, USA.
Carmen MikacenicDivision of Pulmonary, Critical Care, and Sleep Medicine, Center for Lung Biology, University of Washington, 850 Republican St, Seattle, WA, 98109, USA.
Ke-Qin GongDivision of Pulmonary, Critical Care, and Sleep Medicine, Center for Lung Biology, University of Washington, 850 Republican St, Seattle, WA, 98109, USA.
Susanna KosamoDivision of Pulmonary, Critical Care, and Sleep Medicine, Center for Lung Biology, University of Washington, 850 Republican St, Seattle, WA, 98109, USA.
Mark M WurfelDivision of Pulmonary, Critical Care, and Sleep Medicine, Center for Lung Biology, University of Washington, 850 Republican St, Seattle, WA, 98109, USA.
Anne M ManiconeDivision of Pulmonary, Critical Care, and Sleep Medicine, Center for Lung Biology, University of Washington, 850 Republican St, Seattle, WA, 98109, USA. manicone@uw.edu.
University of Washington · USSeattle University · US

Funding

XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI ALI SHOJAIE · 1995 to 2026
$42.5M
Vector and Transgenic Mouse CoreP30DK017047 · NIDDK · UNIVERSITY OF WASHINGTON · PI Sakeneh Zraika · 1986 to 2026
$41.4M
SCCOR in Translational Research in Acute Lung InjuryP50HL073996 · NHLBI · UNIVERSITY OF WASHINGTON · PI MARTIN, THOMAS R · 2003 to 2007
$15.7M
Macrophage Signaling Pathways in Acute Lung Injury and ResolutionR01HL144656 · NHLBI · UNIVERSITY OF WASHINGTON · PI MANICONE, ANNE M. · 2019 to 2022
$2.4M
MMP28 Regulation Of Macrophage Recruitment and PolarizationR01HL116514 · NHLBI · UNIVERSITY OF WASHINGTON · PI MANICONE, ANNE M. · 2014 to 2018
$2.2M
The Role of Alveolar Mononuclear Phagocytes in Acute Respiratory Distress SyndromeK23HL144916 · NHLBI · UNIVERSITY OF WASHINGTON · PI MORRELL, ERIC DOUGLAS · 2019 to 2023
$951k
Influence of TLR1 Polymorphisms on T-Regulatory Cells in ARDSK23HL120896 · NHLBI · UNIVERSITY OF WASHINGTON · PI MIKACENIC, CARMEN R · 2014 to 2018
$881k
NHLBI NIH HHS K23 HL144916NHLBI NIH HHS R01 HL144656NIDDK NIH HHS P30 DK017047NIEHS NIH HHS P30 ES007033NIH HHS K23 HL120896NIH HHS K23 HL144916NIH HHS P50 HL073996NIH HHS R01 HL116514Parker B. Francis Foundation Fellowship
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Lung InjuryAdultAgedBronchoalveolar Lavage FluidFemaleGene Expression RegulationHumansLungMaleMatrix Metalloproteinases, SecretedMiddle AgedRespiratory Distress SyndromeTreatment OutcomeMatrix Metalloproteinases, SecretedMMP28 protein, humanAcute respiratory distress syndromeAlveolar macrophagesMatrix metalloproteinases

Identifiers

PMID32268921
PMCPMC7144344
OpenAlexW3015855688

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.