Evidence map›Paper›PMID 32268539›Full record

ArticleInternational journal of molecular sciences2020

Human DENND1A.V2 Drives

Maria E Teves, Bhavi P Modi, Rewa Kulkarni, Angela X Han, Jamaia S Marks, Mark A Subler, Jolene Windle, Jordan M Newall, Jan M McAllister, Jerome F Strauss

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. The PCOS GWAS Candidate GeneJournal of the Endocrine Society · 2022
    Article
  12. Normal and Premature Adrenarche.Endocrine reviews · 2021
    Review
  13. Genetics of Polycystic Ovary Syndrome: What is New?Endocrinology and metabolism clinics of North America · 2021
    Review
  14. Mid-Gestation lethality ofInternational journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Maria E TevesDepartment of Obstetrics and Gynecology, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID 0000-0001-7035-2202
Bhavi P ModiDepartment of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA.
Rewa KulkarniDepartment of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA.
Angela X HanDepartment of Pathology, Penn State Hershey College of Medicine, Hershey, PA 17033, USA.
Jamaia S MarksDepartment of Pathology, Penn State Hershey College of Medicine, Hershey, PA 17033, USA.
Mark A SublerDepartment of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA.
Jolene WindleDepartment of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA.
Jordan M NewallDepartment of Pathology, Penn State Hershey College of Medicine, Hershey, PA 17033, USA.
Jan M McAllisterDepartment of Pathology, Penn State Hershey College of Medicine, Hershey, PA 17033, USA.
Jerome F StraussDepartment of Obstetrics and Gynecology, Virginia Commonwealth University, Richmond, VA 23298, USA.ORCID 0000-0001-6199-0480
Virginia Commonwealth University · USPenn State Milton S. Hershey Medical Center · US

Funding

Virus Vector Shared ResourceP30CA016059 · NCI · VIRGINIA COMMONWEALTH UNIVERSITY · PI Keri R Maher · 1985 to 2026
$51.0M
VCU Neuroscience Center Core GrantP30NS047463 · NINDS · VIRGINIA COMMONWEALTH UNIVERSITY · PI POVLISHOCK, JOHN T · 2003 to 2013
$5.0M
Functional Analysis of PCOS Candidate GenesR01HD083323 · NICHD · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MCALLISTER, JAN M, STRAUSS, JEROME F · 2016 to 2020
$2.7M
17 ALPHA HYDROXYLASE EXPRESSION IN HUMAN OVARIAN CELLSR01HD033852 · NICHD · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MCALLISTER, JAN M · 1996 to 2010
$2.4M
Mechanism of Metformin Action in Normal and PCOS Theca CellsR01HD058300 · NICHD · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI MCALLISTER, JAN M · 2008 to 2012
$1.7M
NCI NIH HHS P30 CA016059NICHD NIH HHS R01 HD083323NIH HHS R01HD033852NIH HHS R01HD058300NIH HHS R01HD083323NIH HHS U54HD3449NINDS NIH HHS P30 NS047463
6 · The paper itself

Abstract

The

Indexed as

Gene Expression RegulationAdrenal GlandsAndrogensAnimalsBiomarkersBiopsyDeath Domain Receptor Signaling Adaptor ProteinsDisease Models, AnimalDisease SusceptibilityFemaleGenetic VectorsGuanine Nucleotide Exchange FactorsHumansImmunohistochemistryMiceOvaryAndrogensBiomarkersCYP17A1 protein, humanDeath Domain Receptor Signaling Adaptor ProteinsDENND1A protein, humanGuanine Nucleotide Exchange FactorsSteroid 17-alpha-HydroxylaseadrenalsandrogensCyp17a1DENND1Aovariespolycystic ovary syndrome

Identifiers

PMID32268539
PMCPMC7177906
OpenAlexW3014540102

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.