Evidence map›Paper›PMID 32268340›Full record

ArticleNature2020

A general carbonyl alkylative amination for tertiary amine synthesis.

Roopender Kumar, Nils J Flodén, William G Whitehurst, Matthew J Gaunt

Open access · greenAbstract read
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
10.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 190 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. SelectiveThe Journal of organic chemistry · 2025
    Article
  9. Article
  10. Monofluoromethyl Radical Mediated Halogen-Atom Transfer.Journal of the American Chemical Society · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Electrosynthesis of benzyl-Green chemistry : an international journal and green chemistry resource : GC · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. A General Three-Component Alkyl Petasis Boron-Mannich Reaction.Journal of the American Chemical Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Roopender KumarDepartment of Chemistry, University of Cambridge, Cambridge, UK.
Nils J Flodén *Department of Chemistry, University of Cambridge, Cambridge, UK.
William G Whitehurst *Department of Chemistry, University of Cambridge, Cambridge, UK.
Matthew J GauntDepartment of Chemistry, University of Cambridge, Cambridge, UK. mjg32@cam.ac.uk.ORCID http://orcid.org/0000-0002-7214-608X
University of Cambridge · GB

Funding

Swiss National Science Foundation 186730
6 · The paper itself

Abstract

The ubiquity of tertiary alkylamines in pharmaceutical and agrochemical agents, natural products and small-molecule biological probes

Indexed as

AldehydesAlkylationAminationAminesChemistry Techniques, SyntheticLoratadineAldehydesAminesdesloratadineLoratadine

Identifiers

PMID32268340
PMCPMC7116815
OpenAlexW3014276226

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.