Evidence map›Paper›PMID 32268318›Full record

ArticlePhysics in medicine and biology2020

Restarted primal-dual Newton conjugate gradient method for enhanced spatial resolution of reconstructed cone-beam x-ray luminescence computed tomography images.

Peng Gao, Kai Cheng, Emil Schüler, Mengyu Jia, Wei Zhao, Lei Xing

Open access · greenAbstract read
In one paragraph

Article in Physics in medicine and biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Peng GaoDepartment of Radiation Oncology, Stanford University, Stanford, CA 94305, United States of America.ORCID 0000-0003-3253-6996
Kai ChengDepartment of Radiation Oncology, Stanford University, Stanford, CA 94305, United States of America.
Emil SchülerDepartment of Radiation Oncology, Stanford University, Stanford, CA 94305, United States of America.
Mengyu JiaDepartment of Radiation Oncology, Stanford University, Stanford, CA 94305, United States of America.ORCID 0000-0002-3920-0881
Wei ZhaoDepartment of Radiation Oncology, Stanford University, Stanford, CA 94305, United States of America.
Lei XingDepartment of Radiation Oncology, Stanford University, Stanford, CA 94305, United States of America.
Stanford University · USZero to Three · US

Funding

Dual Modality X-ray Luminescence CT for in vivo Cancer ImagingR01CA227713 · NCI · STANFORD UNIVERSITY · PI XING, LEI · 2019 to 2023
$2.9M
Radioluminescence dosimetry solution for precision radiation therapyR01CA223667 · NCI · STANFORD UNIVERSITY · PI XING, LEI · 2018 to 2022
$2.4M
NCI NIH HHS R01 CA223667NCI NIH HHS R01 CA227713
6 · The paper itself

Abstract

Cone-beam x-ray luminescence computed tomography (CB-XLCT) has been proposed as a promising imaging tool, which enables three-dimensional imaging of the distribution of nanophosphors (NPs) in small animals. However, the reconstruction performance is usually unsatisfactory in terms of spatial resolution due to the ill-posedness of the CB-XLCT inverse problem. To alleviate this problem and to achieve high spatial resolution, a reconstruction method consisting of inner and outer iterations based on a restarted strategy is proposed. In this method, the primal-dual Newton conjugate gradient method (pdNCG) is adopted in the inner iterations to get fast reconstruction, which is used for resetting the permission region and increasing the convergence speed of the outer iteration. To assess the performance of the method, both numerical simulation and physical phantom experiments were conducted with a CB-XLCT system. The results demonstrate that compared with conventional reconstruction methods, the proposed re-pdNCG method can accurately and efficiently resolve the adjacent NPs with the least relative error.

Indexed as

Cone-Beam Computed TomographyLuminescenceSignal-To-Noise RatioAlgorithmsImage Processing, Computer-AssistedPhantoms, Imaging

Identifiers

PMID32268318
PMCPMC7594591
OpenAlexW3014661106

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.