Evidence map›Paper›PMID 32268093›Full record

ArticleCell reports2020

TLR9 Sensing of Self-DNA Controls Cell-Mediated Immunity to Listeria Infection via Rapid Conversion of Conventional CD4

Joseph S Dolina, Joey Lee, Ryan Q Griswold, Lara Labarta-Bajo, Sumetha Kannan, Jason A Greenbaum, Nawal Bahia El Idrissi, Margot J Pont, Michael Croft, Stephen P Schoenberger

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Recent Advances in Host Immune Mechanisms AgainstJournal of inflammation research · 2025
    Review
  2. Article
  3. Article
  4. Review
  5. Tregs tango with killer cells in acute infection.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  6. Developmentally distinct CD4Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  7. Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Joseph S DolinaDivision of Developmental Immunology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA. Electronic address: jdolina@lji.org.
Joey LeeDivision of Developmental Immunology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Ryan Q GriswoldDivision of Developmental Immunology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Lara Labarta-BajoDivision of Developmental Immunology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA; Section of Molecular Biology, University of California, San Diego, La Jolla, CA 92093, USA.
Sumetha KannanBioinformatics Core, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Jason A GreenbaumBioinformatics Core, La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
Nawal Bahia El IdrissiDivision of Developmental Immunology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA; Department of Neurogenetics, Academic Medical Center, Amsterdam, the Netherlands.
Margot J PontDivision of Developmental Immunology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Michael CroftDivision of Immune Regulation, La Jolla Institute for Immunology, La Jolla, CA 92037, USA; Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Stephen P SchoenbergerDivision of Developmental Immunology, La Jolla Institute for Immunology, La Jolla, CA 92037, USA. Electronic address: sps@lji.org.
La Jolla Institute for Immunology · USAcademic Medical Center · NL

Funding

Stimulating Neo-Antigen Specific T Cell Responses in Head and Neck CancersU01DE028227 · NIDCR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI GUTKIND, JORGE SILVIO, RAO, ANJANA · 2018 to 2022
$4.6M
Training in Immunological MechanismsT32AI125179 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2016 to 2025
$3.1M
Cellular and Molecular Regulation of CD8+ T cell memoryR01AI107010 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI SCHOENBERGER, STEPHEN PHILIP · 2013 to 2017
$2.2M
Illumina HiSeq 2500 Sequencing SystemS10OD016262 · OD · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI RAO, ANJANA · 2013 to 2013
$600k
FACSAria II Cell SorterS10RR027366 · NCRR · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI CROFT, MICHAEL · 2011 to 2011
$514k
NCRR NIH HHS S10 RR027366NIAID NIH HHS R01 AI107010NIAID NIH HHS T32 AI125179NIDCR NIH HHS U01 DE028227NIH HHS S10 OD016262
6 · The paper itself

Abstract

CD4

Indexed as

AnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell DifferentiationDendritic CellsDNAFemaleImmunity, CellularInterleukin-12Listeria monocytogenesListeriosisLymphocyte ActivationMaleMiceMice, Inbred C57BLMice, TransgenicDNAInterleukin-12Tlr9 protein, mouseToll-Like Receptor 9

Identifiers

PMID32268093
PMCPMC8903023
OpenAlexW3015140850

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.