Evidence map›Paper›PMID 32267681›Full record

ArticleAnalytical chemistry2020

Comparative Analysis of One-Dimensional Protein Fingerprint by Line Shape Enhancement and Two-Dimensional

Korth W Elliott, Houman Ghasriani, Mats Wikström, John P Giddens, Yves Aubin, Frank Delaglio, John P Marino, Luke W Arbogast

Abstract readComparative Study
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
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  10. Review
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  13. Analytical Similarity Assessment of ABP 959 in Comparison with Eculizumab Reference Product.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2021
    Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Korth W ElliottInstitute for Bioscience and Biotechnology Research, National Institute of Standards and Technology, 9600 Gudelsky Drive, Rockville, Maryland 20850, United States.
Houman GhasrianiCenter for Biologics Evaluation, Biologics and Genetic Therapies Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Tunney's Pasture, A/K 2201E, Ottawa, Ontario KIA 0K9, Canada.
Mats WikströmHigher Order Structure Group, Amgen, Incorporated, One Amgen Center Drive, Thousand Oaks, California 91320, United States.ORCID 0000-0002-7982-0962
John P GiddensInstitute for Bioscience and Biotechnology Research, National Institute of Standards and Technology, 9600 Gudelsky Drive, Rockville, Maryland 20850, United States.ORCID 0000-0001-8123-8704
Yves AubinCenter for Biologics Evaluation, Biologics and Genetic Therapies Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Tunney's Pasture, A/K 2201E, Ottawa, Ontario KIA 0K9, Canada.ORCID 0000-0002-8554-0297
Frank DelaglioInstitute for Bioscience and Biotechnology Research, National Institute of Standards and Technology, 9600 Gudelsky Drive, Rockville, Maryland 20850, United States.
John P MarinoInstitute for Bioscience and Biotechnology Research, National Institute of Standards and Technology, 9600 Gudelsky Drive, Rockville, Maryland 20850, United States.
Luke W ArbogastInstitute for Bioscience and Biotechnology Research, National Institute of Standards and Technology, 9600 Gudelsky Drive, Rockville, Maryland 20850, United States.ORCID 0000-0001-6871-450X

Funding

Intramural NIST DOC 9999-NIST
6 · The paper itself

Abstract

The use of NMR spectroscopy has emerged as a premier tool to characterize the higher order structure of protein therapeutics and in particular IgG1 monoclonal antibodies (mAbs). Due to their large size, traditional

Indexed as

Nuclear Magnetic Resonance, BiomolecularCarbon IsotopesImmunoglobulin GProtonsCarbon IsotopesImmunoglobulin GProtons

Identifiers

PMID32267681
PMCPMC8054654

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.