Evidence map›Paper›PMID 32267192›Full record

ArticleJournal of psychopharmacology (Oxford, England)2020

Evaluating the co-use of opioids and cannabis for pain among current users using hypothetical purchase tasks.

Cecilia L Bergeria, Sean B Dolan, Matthew W Johnson, Claudia M Campbell, Kelly E Dunn

Open access · greenAbstract read
In one paragraph

Article in Journal of psychopharmacology (Oxford, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
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  5. Human laboratory models of reward in substance use disorder.Pharmacology, biochemistry, and behavior · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Cecilia L BergeriaDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, USA.ORCID 0000-0002-8183-1273
Sean B DolanDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, USA.ORCID 0000-0003-1828-9589
Matthew W JohnsonDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, USA.
Claudia M CampbellDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, USA.
Kelly E DunnDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, USA.
Johns Hopkins University · US

Funding

HUMAN BEHAVIORAL PHARMACOLOGY OF SUBSTANCE ABUSET32DA007209 · NIDA · JOHNS HOPKINS UNIVERSITY · PI Eric C. Strain, Elise M Weerts · 1985 to 2026
$12.9M
Using Cannabinoids to Enhance Opioid Analgesic Effects in HumansR01DA040644 · NIDA · JOHNS HOPKINS UNIVERSITY · PI CAMPBELL, CLAUDIA MICHELLE, DUNN, KELLY E · 2016 to 2021
$3.4M
A118G SNP and OPRM1 Gene Opioid-Mediated Effects in HumansR01DA035246 · NIDA · JOHNS HOPKINS UNIVERSITY · PI DUNN, KELLY E · 2014 to 2018
$3.2M
Opioid and cannabinoid combinations in laboratory and clinical painR01DA042751 · NIDA · JOHNS HOPKINS UNIVERSITY · PI CAMPBELL, CLAUDIA MICHELLE, DUNN, KELLY E · 2017 to 2020
$2.2M
NIDA NIH HHS R01 DA035246NIDA NIH HHS R01 DA040644NIDA NIH HHS R01 DA042751NIDA NIH HHS T32 DA007209
6 · The paper itself

Abstract

backgroundCannabinoids may potentiate opioid analgesia and therefore could be used to reduce reliance on opioids for analgesia.

aimsThe current study evaluated whether the concurrent availability of cannabis influences opioid consumption using a behavioral economic demand framework.

methodsAn online survey assessed cannabis and opioid use frequency and dependence measures, pain severity, and demand for both cannabis and opioids alone and when concurrently available using hypothetical purchase tasks. Adults reporting current use of opioids for pain management and past 30-day cannabis exposure (

resultsDemand intensity was significantly reduced and demand elasticity was significantly increased for both cannabis and opioids when the alternate commodity was available, although the reductions in cannabis consumption were more pronounced than they were for opioid consumption in the presence of the alternate commodity.

conclusionsThese data provide behavioral economic evidence that cannabis access may modestly reduce demand for opioids in persons who have pain. Additional clinical studies that evaluate the analgesic effects of cannabis and cannabis-opioid effects on pain are warranted.

Indexed as

AdultAnalgesics, OpioidCommerceFemaleHumansMaleMarijuana UseOpioid-Related DisordersPainSurveys and QuestionnairesYoung AdultAnalgesics, Opioidbehavioral economicscannabisdemandOpioidspain

Identifiers

PMID32267192
PMCPMC7246164
OpenAlexW3014229475

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.