ArticleJournal of anatomy2020
Biological clocks and incremental growth line formation in dentine.
Article in Journal of anatomy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Fetal exposure to persistent organic pollutants and childhood autism risk.Environmental research · 2026Article
- Histological analysis of incremental markings and crown growth characteristics in mandibular first molars of the red fox, Vulpes vulpes (Canidae, Mammalia).Journal of anatomy · 2026Article
- p75NTR Promotes Circadian-Driven Mineralization During Tooth Development via CK2/PER2 Pathway.Cell proliferation · 2026Article
- Circadian rhythm disruption impairs time-dependent dentine regeneration and reprograms the late-stage dental proteome in a mouse pulp injury model.Frontiers in pharmacology · 2026Article
- Variation in Modern Human Deciduous Molar Enamel Formation Time.American journal of biological anthropology · 2025Article
- The circadian clock in enamel development.International journal of oral science · 2024Review
- Wild boar versus domestic pig-Deciphering of crown growth in porcine second molars.Journal of anatomy · 2023Article
- Using SXRF and LA-ICP-TOFMS to Explore Evidence of Treatment and Physiological Responses to Leprosy in Medieval Denmark.Biology · 2023Article
- p75NTR promotes tooth rhythmic mineralization via upregulation of BMAL1/CLOCK.Frontiers in cell and developmental biology · 2023Article
- Clock genes are expressed in cementum and regulate the proliferation and mineralization of cementoblasts.In vitro cellular & developmental biology. Animal · 2023Article
- Evolution of amniote dentine apposition rates.Biology letters · 2022Article
- A potential role ofFrontiers in physiology · 2022Article
- Circadian clock-A promising scientific target in oral science.Frontiers in physiology · 2022Review
- Characterization of short-period and long-period incremental markings in porcine enamel and dentine-Results of a fluorochrome labelling study in wild boar and domestic pigs.Journal of anatomy · 2021Article
- Using primary teeth and archived dried spots for exposomic studies in children: Exploring new paths in the environmental epidemiology of pediatric cancer.BioEssays : news and reviews in molecular, cellular and developmental biology · 2021Review
- Spatial-Temporal Patterns and Inflammatory Factors of Bone Matrix Remodeling.Stem cells international · 2021Review
- Growth and development of the third permanent molar in Paranthropus robustus from Swartkrans, South Africa.Scientific reports · 2020Article
- Biological clocks and incremental growth line formation in dentine.Journal of anatomy · 2020Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 4 countries.
Funding
Abstract
Dentine- and enamel-forming cells secrete matrix in consistent rhythmic phases, resulting in the formation of successive microscopic growth lines inside tooth crowns and roots. Experimental studies of various mammals have proven that these lines are laid down in subdaily, daily (circadian), and multidaily rhythms, but it is less clear how these rhythms are initiated and maintained. In 2001, researchers reported that lesioning the so-called master biological clock, the suprachiasmatic nucleus (SCN), halted daily line formation in rat dentine, whereas subdaily lines persisted. More recently, a key clock gene (Bmal1) expressed in the SCN in a circadian manner was also found to be active in dentine- and enamel- secretory cells. To probe these potential neurological and local mechanisms for the production of rhythmic lines in teeth, we reexamined the role of the SCN in growth line formation in Wistar rats and investigated the presence of daily lines in Bmal1 knockout mice (Bmal1
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.