SynthesisArchives of orthopaedic and trauma surgery2021
Open versus minimally-invasive surgery for Achilles tendon rupture: a meta-analysis study.
Synthesis in Archives of orthopaedic and trauma surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 7 syntheses or guidelines pooled it, 94 citations in OpenAlex.
- Minimally invasive versus open surgery for acute achilles tendon rupture: an umbrella review of systematic reviews and meta-analyses.Frontiers in surgery · 2025Pooled it
- Mini-open versus percutaneous surgical repair for acute Achilles tendon rupture: a systematic review and meta-analysis.International orthopaedics · 2025Pooled it
- [Surgical or non-operative treatment of acute Achilles tendon rupture : What does the current literature say?]Orthopadie (Heidelberg, Germany) · 2024Pooled it
- Surgical vs. nonoperative treatment for acute Achilles' tendon rupture: a meta-analysis of randomized controlled trials.Frontiers in surgery · 2024Pooled it
- Lower re-rupture rates but higher complication rates following surgical versus conservative treatment of acute achilles tendon ruptures: a systematic review of overlapping meta-analyses.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Pooled it
- Pooled it
- Comparison of clinical outcomes associated with arthroscopic cyst wall preservation or resection in the treatment of popliteal cyst: a systematic review and meta-analysis.Archives of orthopaedic and trauma surgery · 2021Pooled it
- Open surgery and minimally invasive repair of acute Achilles tendon rupture: stratified outcomes based on immobilization duration in a prospective cohort study.Journal of orthopaedic surgery and research · 2025Trial
- Outcomes of early versus late functional weight-bearing after the acute Achilles tendon rupture repair with minimally invasive surgery: a randomized controlled trial.Archives of orthopaedic and trauma surgery · 2023Trial
- Patient-Centered Outcomes After Minimally Invasive Internal Splinting Versus Open Achilles Tendon Repair: Comparable Clinically Meaningful Recovery at 12 Months.Journal of clinical medicine · 2026Article
- Biomimetic Constructs for Achilles Tendon Regeneration and their Translation to Human Medicine.Tissue engineering and regenerative medicine · 2026Review
- Morphology-based classification program of Achilles tendon ruptures using magnetic resonance imaging: a mapping study.BMC musculoskeletal disorders · 2026Observational
- Rapamycin reduces peritendinous fibrosis but has a limited effect on intratendinous healing in a rodent Achilles tendon injury model.Scientific reports · 2026Article
- Endoscopic Assistance in Minimally Invasive Repair of Acute Achilles Ruptures: A Prospective Observational Study Comparing Endoscopic-Assisted, Minimally Invasive, and Open Techniques.Journal of clinical medicine · 2025Article
- Return to Play After Achilles Tendon Rupture: Comparing Operative and Nonoperative Approaches in Athletes.Cureus · 2025Review
- Knotted or knotless? Efficacy analysis of the percutaneous Achilles repair system (PARS) for acute Achilles tendon ruptures: a retrospective cohort study.Journal of orthopaedic surgery and research · 2025Article
- Successful functional outcomes and return to sport rate can be achieved after surgery for acute Achilles tendon rupture: A systematic review.Journal of experimental orthopaedics · 2025Review
- Association of Surgical Timing With Complications and Patient-Reported Outcomes After Achilles Tendon Repair.Orthopaedic journal of sports medicine · 2025Article
- The impact of Achilles tendon thickness and Kager's fat pad thickness on clinical and functional outcomes following open surgical repair of acute Achilles tendon rupture.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- 2-Octyl cyanoacrylate adjuvant use in calcaneal tendon repair: A comparative experimental study in rabbits.Journal of experimental orthopaedics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDespite the presence of various different surgical procedures, the preferable technique for repair of acute Achilles tendon ruptures is unknown and, therefore, object of discussions. The purpose of this meta-analysis was to compare clinical outcomes and complication-rates between the minimally invasive and the standard open repair of acute Achilles tendon ruptures. MATERIALS AND
methodsThis meta-analysis was performed according to the PRISMA guidelines. In September 2019 the main databases were accessed. All clinical trials of evidence level I to III comparing minimally invasive vs. open surgery of Achilles tendon rupture were included in the present study. Only articles reporting quantitative data under the outcomes of interest were included. Missing data under the outcomes of interest warranted the exclusion from the present work. For the statistical analysis we referred to the Review Manager Software Version 5.3. (The Nordic Cochrane Centre, Copenhagen). Continuous data were analysed through the inverse variance method. For the effect estimate the mean difference was used. Dichotomous data were analysed through the Mante-Haenszel method via odd ratio effect measure. The confidence interval was set at 95% in all the comparisons. Values of P < 0.05 were considered statistically significant.
resultsA total of 25 articles were included for meta-analysis. The funnel plot revealed poor data dispersion, attesting to this study a low risk of publication bias. The quality of the methodological assessment was moderate. Data from 2223 (1055 open, 1168 minimally invasive) surgical procedures were extracted. The mean follow-up was of 24.29 ± 22.4 months. The open group reported a lower value of post-operative palpable knot at last follow-up and a lower rate of sural nerve palsy. In the minimally-invasive group a shorter surgery duration and a lower rate of post-operative wound necrosis and reduced risk of wound scarring and adhesions has been evidenced. The minimally-invasive cohort detected the lowest values of superficial and deep infections. In both groups no significant difference was shown in re-rupture rate.
conclusionsCompared to the minimally-invasive Achilles tendon reconstruction, the open procedure evidenced a lower rate of sural nerve palsy and postoperative palpable knot, whereas in the minimally-invasive reconstruction group quicker surgery duration, a lower rate of post-operative wound necrosis, superficial and deep infections and less scar tissue adhesions could be observed. No relevant discrepancies were detected among the two techniques in terms of post-operative re-rupture.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.