Evidence map›Paper›PMID 32266234›Full record

ArticleFrontiers in bioengineering and biotechnology2020

Harnessing Fiber Diameter-Dependent Effects of Myoblasts Toward Biomimetic Scaffold-Based Skeletal Muscle Regeneration.

Naagarajan Narayanan, Chunhui Jiang, Chao Wang, Gözde Uzunalli, Nicole Whittern, Da Chen, Owen G Jones, Shihuan Kuang, Meng Deng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 71 citations in OpenAlex.

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  12. Porous biomaterial scaffolds for skeletal muscle tissue engineering.Frontiers in bioengineering and biotechnology · 2023
    Review
  13. Nanomaterial for Skeletal Muscle Regeneration.Tissue engineering and regenerative medicine · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Naagarajan NarayananDepartment of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN, United States.
Chunhui JiangDepartment of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN, United States.
Chao WangDepartment of Animal Sciences, Purdue University, West Lafayette, IN, United States.
Gözde UzunalliDepartment of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN, United States.
Nicole WhitternDepartment of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN, United States.
Da ChenDepartment of Food Sciences, Purdue University, West Lafayette, IN, United States.
Owen G JonesDepartment of Food Sciences, Purdue University, West Lafayette, IN, United States.
Shihuan KuangDepartment of Animal Sciences, Purdue University, West Lafayette, IN, United States.
Meng DengDepartment of Agricultural and Biological Engineering, Purdue University, West Lafayette, IN, United States.
Purdue University West Lafayette · US

Funding

PTEN Function in Satellite CellsR01AR071649 · NIAMS · PURDUE UNIVERSITY · PI KUANG, SHIHUAN · 2017 to 2021
$1.7M
Engineering A Biomaterial Niche of Satellite Cells for Skeletal Muscle RegenerationR03AR068108 · NIAMS · PURDUE UNIVERSITY · PI DENG, MENG · 2016 to 2018
$227k
NIAMS NIH HHS R01 AR071649NIAMS NIH HHS R03 AR068108
6 · The paper itself

Abstract

Regeneration of skeletal muscles is limited in cases of volumetric muscle loss and muscle degenerative diseases. Therefore, there is a critical need for developing strategies that provide cellular and structural support for skeletal muscle regeneration. In the present work, a bioengineered cell niche composed of mechanically competent aligned polyester fiber scaffolds is developed to mimic the oriented muscle fiber microenvironment by electrospinning poly(lactide-

Indexed as

electrospun fibersmyoblastspolyestersskeletal muscletopography

Identifiers

PMID32266234
PMCPMC7105569
OpenAlexW3013179227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.