Evidence map›Paper›PMID 32266222›Full record

ReviewFrontiers in bioengineering and biotechnology2020

MicroRNA Mediated Cardioprotection - Is There a Path to Clinical Translation?

Timo Z Nazari-Shafti, Vasileios Exarchos, Héctor Rodriguez Cetina Biefer, Nikola Cesarovic, Heike Meyborg, Volkmar Falk, Maximilian Y Emmert

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Empagliflozin modulates microRNA expression in human primary cardiomyocytes under CoClInternational journal of cardiology. Cardiovascular risk and prevention · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Timo Z Nazari-ShaftiDepartment for Cardiovascular and Thoracic Surgery, German Heart Center Berlin, Berlin, Germany.
Vasileios ExarchosDepartment for Cardiovascular and Thoracic Surgery, German Heart Center Berlin, Berlin, Germany.
Héctor Rodriguez Cetina BieferDepartment for Cardiovascular and Thoracic Surgery, German Heart Center Berlin, Berlin, Germany.
Nikola CesarovicDepartment for Cardiovascular and Thoracic Surgery, German Heart Center Berlin, Berlin, Germany.
Heike MeyborgDepartment for Cardiovascular and Thoracic Surgery, German Heart Center Berlin, Berlin, Germany.
Volkmar FalkDepartment for Cardiovascular and Thoracic Surgery, German Heart Center Berlin, Berlin, Germany.
Maximilian Y EmmertDepartment for Cardiovascular and Thoracic Surgery, German Heart Center Berlin, Berlin, Germany.
Berlin Heart (Germany) · DEDeutsches Herzzentrum der Charité · DEBerlin Institute of Health at Charité - Universitätsmedizin Berlin · DEETH Zurich · CHUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past 20 years, there have been several approaches to achieve cardioprotection or cardiac regeneration using a vast variety of cell therapies and remote ischemic pre-conditioning (RIPC). To date, substantial proof that either cell therapy or RIPC has the potential for clinically relevant cardiac repair or regeneration of cardiac tissue is still pending. Preclinical trials indicate that the secretome of cells

Indexed as

cardioprotectionextracellular vesiclesmicroRNAsecond generation cell therapiessecretometranslation

Identifiers

PMID32266222
PMCPMC7099408
OpenAlexW3010837736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.