Evidence map›Paper›PMID 32266211›Full record

ArticleFrontiers in chemistry2020

Functionalized Graphene Oxide Thin Films for Anti-tumor Drug Delivery to Melanoma Cells.

Livia E Sima, Gabriela Chiritoiu, Irina Negut, Valentina Grumezescu, Stefana Orobeti, Cristian V A Munteanu, Felix Sima, Emanuel Axente

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Livia E SimaDepartment of Molecular Cell Biology, Institute of Biochemistry, Romanian Academy, Bucharest, Romania.
Gabriela ChiritoiuDepartment of Molecular Cell Biology, Institute of Biochemistry, Romanian Academy, Bucharest, Romania.
Irina NegutPhotonic Investigations Laboratory, Center for Advanced Laser Technologies, National Institute for Lasers, Plasma and Radiation Physics, Magurele, Romania.
Valentina GrumezescuPhotonic Investigations Laboratory, Center for Advanced Laser Technologies, National Institute for Lasers, Plasma and Radiation Physics, Magurele, Romania.
Stefana OrobetiDepartment of Molecular Cell Biology, Institute of Biochemistry, Romanian Academy, Bucharest, Romania.
Cristian V A MunteanuDepartment of Bioinformatics and Structural Biochemistry, Institute of Biochemistry, Romanian Academy, Bucharest, Romania.
Felix SimaPhotonic Investigations Laboratory, Center for Advanced Laser Technologies, National Institute for Lasers, Plasma and Radiation Physics, Magurele, Romania.
Emanuel AxentePhotonic Investigations Laboratory, Center for Advanced Laser Technologies, National Institute for Lasers, Plasma and Radiation Physics, Magurele, Romania.
National Institute for Laser Plasma and Radiation Physics · ROInstitute of Biochemistry · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since Graphene discovery, their associated derivate nanomaterials, Graphene Oxide (GO) and reduced-GO were in the forefront of continuous developments in bio-nano-technology due to unique physical-chemical properties. Although GO nano-colloids (GON) were proposed as drug release matrix for targeting cancer cells, there is still a concern regarding its cytotoxicity issues. In this study, we report on the fabrication of functional GON bio-coatings by Matrix-Assisted Pulsed Laser Evaporation (MAPLE) to be used as drug carriers for targeting melanoma cells. We first performed a thorough

Indexed as

cytotoxicitydrug deliverygraphene oxideMAPLEmelanomananomaterialsthin films

Identifiers

PMID32266211
PMCPMC7104690
OpenAlexW3014015413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.