Evidence map›Paper›PMID 32266185›Full record

ArticleFrontiers in pediatrics2020

Volume Guarantee High-Frequency Oscillatory Ventilation in Preterm Infants With RDS: Tidal Volume and DCO

Funda Tuzun, Burak Deliloglu, Merve Meryem Cengiz, Burcin Iscan, Nuray Duman, Hasan Ozkan

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06719284 (Crossover Study of the Cerebral Blood Flow and Cardiac Output At Different Targeted Tidal Volumes During High Frequency Oscillation with Volume Targeted Ventilation), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06719284 narecruitingnot on this mapstarted 2025, after this paper: background citation

Crossover Study of the Cerebral Blood Flow and Cardiac Output At Different Targeted Tidal Volumes During High Frequency Oscillation with Volume Targeted Ventilation (HFO&VTV)

TypeinterventionalSponsorKing's College Hospital NHS TrustRan2025 to 2026Enrolled27ConditionsHigh Frequency Oscillation, Volume Targeted VentilationArmsHFO&VTV at targeted tidal volumes of 1.5, 2.0 and 2.5 ml/kg in random order, HFOV at the settings applied prior to the study
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  9. High-frequency oscillatory ventilation with or without volume guarantee during neonatal transport.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Observational
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  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Funda TuzunDivision of Neonatology, Department of Pediatrics, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
Burak DelilogluDivision of Neonatology, Department of Pediatrics, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
Merve Meryem CengizDivision of Neonatology, Department of Pediatrics, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
Burcin IscanDivision of Neonatology, Department of Pediatrics, Tinaztepe University Faculty of Medicine, Izmir, Turkey.
Nuray DumanDivision of Neonatology, Department of Pediatrics, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
Hasan OzkanDivision of Neonatology, Department of Pediatrics, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey.
Dokuz Eylül University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High frequency oscillatory ventilation with volume-guarantee (HFOV-VG) is a promising lung protective ventilator mode for the treatment of respiratory failure in newborns. However, indicators of optimal ventilation during HFOV-VG mode are not identified yet. In this study, we aimed to evaluate optimal high-frequency tidal volume (VThf) and the dissociation coefficient of CO

Indexed as

DCO2frequencyHFOVlung-protective strategieslung recruitmentRDSvolume guaranteeVThf

Identifiers

PMID32266185
PMCPMC7105735
OpenAlexW3014050286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.