Evidence map›Paper›PMID 32266103›Full record

ArticleAmerican journal of cancer research2020

MicroRNA-590-3p inhibits invasion and metastasis in triple-negative breast cancer by targeting Slug.

Meisi Yan, Leiguang Ye, Xinxin Feng, Runze Shi, Zhen Sun, Zhigao Li, Tong Liu

Open access · greenAbstract read
In one paragraph

Article in American journal of cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Meisi YanDepartment of Pathology, Harbin Medical University Harbin 150081, China.
Leiguang YeDepartment of Oncology, Harbin Medical University Cancer Hospital Harbin 150000, China.
Xinxin FengDepartment of Pathology, Harbin Medical University Harbin 150081, China.
Runze ShiDepartment of Breast Surgery, Harbin Medical University Cancer Hospital Harbin 150000, China.
Zhen SunDepartment of Molecular and Cellular Biology, Baylor College of Medical TX 77030, United States.
Zhigao LiDepartment of Breast Surgery, Harbin Medical University Cancer Hospital Harbin 150000, China.
Tong LiuDepartment of Breast Surgery, Harbin Medical University Cancer Hospital Harbin 150000, China.
Harbin Medical University · CNThe University of Texas MD Anderson Cancer Center · USBaylor College of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

miR-590-3p acts as a tumor suppressor in glioblastoma multiform, medulloblastoma, hepatocellular carcinoma, and nephroblastoma. Here, we studied the role of miR-590-3p in triple-negative breast cancer (TNBC). The miR-590-3p levels in TNBC specimens were significantly lower than those in non-TNBC specimens. Overexpression of miR-590-3p significantly inhibited migration and invasion of TNBC cells and lung metastasis

Indexed as

cancer metastasismiR-590-3pSlugTriple-negative breast cancer

Identifiers

PMID32266103
PMCPMC7136920
OpenAlexW3015185102

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.