Evidence map›Paper›PMID 32266076›Full record

ArticleJournal of pharmaceutical health care and sciences2020

Emergency intensive care unit pharmacist's intervention may reduce time to four-factor prothrombin complex concentrate administration: a retrospective study.

Shoichi Imanaka, Tatsuro Kuwabara, Hiroto Ikeda, Yasufumi Miyake, Hiromi Enomoto, Tetsuya Sakamoto, Nobuhiro Yasuno

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pharmaceutical health care and sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shoichi Imanaka1Pharmaceutical Department, Teikyo University School of Medicine Hospital, 2-11-1 Kaga, Itabashi-Ku, Tokyo, 173-8605 Japan.
Tatsuro Kuwabara1Pharmaceutical Department, Teikyo University School of Medicine Hospital, 2-11-1 Kaga, Itabashi-Ku, Tokyo, 173-8605 Japan.
Hiroto Ikeda2Department of Emergency Medicine, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-Ku, Tokyo, 173-8605 Japan.
Yasufumi Miyake2Department of Emergency Medicine, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-Ku, Tokyo, 173-8605 Japan.
Hiromi Enomoto1Pharmaceutical Department, Teikyo University School of Medicine Hospital, 2-11-1 Kaga, Itabashi-Ku, Tokyo, 173-8605 Japan.
Tetsuya Sakamoto2Department of Emergency Medicine, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-Ku, Tokyo, 173-8605 Japan.
Nobuhiro Yasuno1Pharmaceutical Department, Teikyo University School of Medicine Hospital, 2-11-1 Kaga, Itabashi-Ku, Tokyo, 173-8605 Japan.
Teikyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFour-factor prothrombin complex concentrate (4F-PCC) must be administered as soon as possible, and in our emergency intensive care unit (EICU), pharmacists are available on weekdays for consultation on expediting 4F-PCC administration. Although recent reports have described a reduction in time to 4F-PCC administration, few studies have addressed if this is because of EICU pharmacist's intervention, and there are no such studies in Japan. Therefore, we aimed to examine whether EICU pharmacist's intervention reduced time to 4F-PCC administration.

methodsThis single-center retrospective cohort study was conducted from December 2017 to May 2019. We enrolled patients who received 4F-PCC due to major bleeding or requirement of urgent surgical/invasive procedures (

resultsThe median time from patient presentation to the EICU to 4F-PCC administration (103 min vs. 111 min,

conclusionsEICU pharmacist's intervention improves the process from 4F-PCC prescription to administration and can reduce time to 4F-PCC administration.

Indexed as

Anticoagulation reversalPharmacistProthrombin complex concentrateTime reductionWarfarin

Identifiers

PMID32266076
PMCPMC7118855
OpenAlexW3014617518

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.