ArticleFrontiers in immunology2020
Infant Alveolar Macrophages Are Unable to Effectively Contain
Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Gravidity influences distinct transcriptional profiles of maternal and fetal placental macrophages at term.Frontiers in immunology · 2024Article
- New Insights in Immunometabolism in Neonatal Monocytes and Macrophages in Health and Disease.International journal of molecular sciences · 2023Review
- Plasma chemokines CXCL10 and CXCL9 as potential diagnostic markers of drug-sensitive and drug-resistant tuberculosis.Scientific reports · 2023Article
- Airway macrophages display decreased expression of receptors mediating and regulating scavenging in early cystic fibrosis lung disease.Frontiers in immunology · 2023Article
- Biology of lung macrophages in health and disease.Immunity · 2022Review
- Surveying the Epigenetic Landscape of Tuberculosis in Alveolar Macrophages.Infection and immunity · 2022Review
- Review
- Immunopathogenesis in HIV-associated pediatric tuberculosis.Pediatric research · 2022Review
- Integrative Analysis of Human Macrophage Inflammatory Response Related toFrontiers in immunology · 2021Article
- The Warburg Effect Occurs Rapidly in Stimulated Human Adult but Not Umbilical Cord Blood Derived Macrophages.Frontiers in immunology · 2021Article
- Local Pulmonary Immunological Biomarkers in Tuberculosis.Frontiers in immunology · 2021Review
- Aging increases the systemic molecular degree of inflammatory perturbation in patients with tuberculosis.Scientific reports · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Infants are more likely to develop lethal disseminated forms of tuberculosis compared with older children and adults. The reasons for this are currently unknown. In this study we test the hypothesis that antimycobacterial function is impaired in infant alveolar macrophages (AMϕs) compared with those of adults. We develop a method of obtaining AMϕs from healthy infants using rigid bronchoscopy and incubate the AMϕs with live virulent
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.