Evidence map›Paper›PMID 32265924›Full record

ArticleFrontiers in immunology2020

A Shared Regulatory Element Controls the Initiation of

Christelle Harly, Devin Kenney, Yueqiang Wang, Yi Ding, Yongge Zhao, Parirokh Awasthi, Avinash Bhandoola

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Pre-division TCF1 drop determines long-term CD8 T cell fates.bioRxiv : the preprint server for biology · 2025
    Article
  6. Article
  7. Article
  8. Transcriptional network dynamics in early T cell development.The Journal of experimental medicine · 2024
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Circulating IRF8-expressing CD123Trends in immunology · 2023
    Review
  14. Article
  15. TCF-1 Is Required for CD4 T Cell Persistence Functions during AlloImmunity.International journal of molecular sciences · 2023
    Article
  16. Review
  17. Purification of Bone Marrow Precursors to T Cells and ILCs.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  18. Early Development of Innate Lymphoid Cells.Methods in molecular biology (Clifton, N.J.) · 2023
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Christelle HarlyT-Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, MD, United States.
Devin KenneyT-Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, MD, United States.
Yueqiang WangT-Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, MD, United States.
Yi DingT-Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, MD, United States.
Yongge ZhaoT-Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, MD, United States.
Parirokh AwasthiLaboratory Animal Sciences Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, National Institute of Health, Frederick, MD, United States.
Avinash BhandoolaT-Cell Biology and Development Unit, Laboratory of Genome Integrity, Center for Cancer Research, National Cancer Institute, National Institute of Health, Bethesda, MD, United States.
Center for Cancer Research · USNational Cancer Institute · USLeidos (United States) · US

Funding

T cell Development and RegenerationZIABC011633 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI BHANDOOLA, AVINASH · 2015 to 2025
$20.5M
6 · The paper itself

Abstract

The transcription factor TCF-1 (encoded by

Indexed as

AnimalsCell DifferentiationCells, CulturedGene Expression RegulationHepatocyte Nuclear Factor 1-alphaImmunity, InnateLymphocyte ActivationLymphocytesMiceMice, Inbred C57BLMice, KnockoutRegulatory Elements, TranscriptionalT-LymphocytesHepatocyte Nuclear Factor 1-alphaHnf1a protein, mousedevelopmentenhancerinnate lymphoid cellsT cellsTCF-1Tcf7

Identifiers

PMID32265924
PMCPMC7099406
OpenAlexW3010712076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.