Evidence map›Paper›PMID 32265865›Full record

ArticleFrontiers in microbiology2020

Exploiting Zebrafish Xenografts for Testing the

Macarena A Varas, Carlos Muñoz-Montecinos, Violeta Kallens, Valeska Simon, Miguel L Allende, Andrés E Marcoleta, Rosalba Lagos

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

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  14. Application Value of Antimicrobial Peptides in Gastrointestinal Tumors.International journal of molecular sciences · 2023
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  19. Colicins and Microcins Produced byInternational journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Macarena A VarasLaboratorio de Biología Estructural y Molecular BEM, Departamento de Biología, Facultad de Ciencias, Universidad de Chile, Santiago, Chile.
Carlos Muñoz-MontecinosDepartamento de Biología, Facultad de Ciencias, FONDAP Center for Genome Regulation, Universidad de Chile, Santiago, Chile.
Violeta KallensDepartamento de Biología, Facultad de Ciencias, FONDAP Center for Genome Regulation, Universidad de Chile, Santiago, Chile.
Valeska SimonLaboratorio de Inmunología, Departamento de Biología, Facultad de Ciencias, Universidad de Chile, Santiago, Chile.
Miguel L AllendeDepartamento de Biología, Facultad de Ciencias, FONDAP Center for Genome Regulation, Universidad de Chile, Santiago, Chile.
Andrés E MarcoletaLaboratorio de Biología Estructural y Molecular BEM, Departamento de Biología, Facultad de Ciencias, Universidad de Chile, Santiago, Chile.
Rosalba LagosLaboratorio de Biología Estructural y Molecular BEM, Departamento de Biología, Facultad de Ciencias, Universidad de Chile, Santiago, Chile.
University of Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the approaches to address cancer treatment is to develop new drugs not only to obtain compounds with less side effects, but also to have a broader set of alternatives to tackle the resistant forms of this pathology. In this regard, growing evidence supports the use of bacteria-derived peptides such as bacteriocins, which have emerged as promising anti-cancer molecules. In addition to test the activity of these molecules on cancer cells in culture, their

Indexed as

antitumorigenic peptidebacteriocincolorectal cancercytotoxicityhuman cell linesKlebsiella pneumoniaemicrocin E492zebrafish xenograft

Identifiers

PMID32265865
PMCPMC7096547
OpenAlexW3011905210

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.