Evidence map›Paper›PMID 32265853›Full record

ArticleFrontiers in microbiology2020

RIPK3 Promotes JEV Replication in Neurons

Peiyu Bian, Chuantao Ye, Xuyang Zheng, Chuanyu Luo, Jiali Yang, Mengyuan Li, Yuan Wang, Jing Yang, Yun Zhou, Fanglin Zhang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

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  18. Potential for Protein Kinase Pharmacological Regulation inInternational journal of molecular sciences · 2020
    Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Peiyu BianDepartment of Infectious Diseases, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Chuantao YeDepartment of Infectious Diseases, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Xuyang ZhengDepartment of Infectious Diseases, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Chuanyu LuoPathogenic Biology, Medical College of Yan'an University, Yan'an, China.
Jiali YangKey Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an, China.
Mengyuan LiDepartment of Infectious Diseases, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Yuan WangDepartment of Microbiology, School of Preclinical Medicine, Air Force Medical University, Xi'an, China.
Jing YangDepartment of Microbiology, School of Preclinical Medicine, Air Force Medical University, Xi'an, China.
Yun ZhouDepartment of Infectious Diseases, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Fanglin ZhangDepartment of Microbiology, School of Preclinical Medicine, Air Force Medical University, Xi'an, China.
Jianqi LianDepartment of Infectious Diseases, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Ying ZhangDepartment of Infectious Diseases, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Zhansheng JiaDepartment of Infectious Diseases, Tangdu Hospital, Air Force Medical University, Xi'an, China.
Yingfeng LeiDepartment of Microbiology, School of Preclinical Medicine, Air Force Medical University, Xi'an, China.
Air Force Medical University · CNNorthwest University · CNYan'an University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Japanese encephalitis virus (JEV), the leading cause of viral encephalitis in Asia, is neurovirulent and neuroinvasive. Neurons are the main target of JEV infection and propagation. Receptor interacting serine/threonine-protein kinase 3 (RIPK3) has been reported to contribute to neuroinflammation and neuronal death in many central nervous system diseases. In this study, we found that the progression of JE was alleviated in RIPK3-knockout (RIPK3

Indexed as

cellular innate immune responseinterferon-induced protein 44-like gene (IFI44L)Japanese encephalitis virus (JEV)neuronsreceptor interacting serine/threonine-protein kinase 3 (RIPK3)

Identifiers

PMID32265853
PMCPMC7105639
OpenAlexW3014027022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.