ArticleFrontiers in pharmacology2020
An Increasing Trend in the Prevalence of Polypharmacy in Sweden: A Nationwide Register-Based Study.
Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
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Who cites it
59 citing papers in PubMed, 95 citations in OpenAlex.
- Roles and perceived responsibilities of investigators and pharmacists in the monitoring of drug-drug interactions in clinical trials - a mixed methods study.Exploratory research in clinical and social pharmacy · 2026Article
- Pharmacists' role in interventions addressing excessive polypharmacy: a scoping review.International journal of clinical pharmacy · 2026Article
- Pharmacist-Led Deprescribing Interventions for Older Adults with Polypharmacy: A Retrospective Cohort Study of Community Pharmacy Practice in Japan.Drugs & aging · 2026Article
- Australian Polypharmacy Trends Between 2013 and 2024: A Repeated Cross-Sectional Study in the Adult Population.Drugs & aging · 2026Article
- Understanding Undergraduate Medicines Optimisation Education and Its Importance; a Realist Evaluation.Perspectives on medical education · 2026Article
- Interventions to improve adherence to lipid-lowering drugs: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- The Prevalence of Polypharmacy and the Contribution of Age, Period, and Cohort Effects in Sweden From 2006 to 2020.Health science reports · 2025Article
- Family Involvement During Patient Hospitalisation-Developing and Testing a Clinical Decision Aid.Scandinavian journal of caring sciences · 2025Article
- Pharmacotherapeutic actions related to drug interaction alerts - a questionnaire study among Swedish hospital interns and residents in family medicine.European journal of clinical pharmacology · 2025Article
- Xerostomia in primary care: a register-based study of prevalence, medication categories, and associated risk factors.Frontiers in oral health · 2025Article
- Proceedings of the Canadian Medication Appropriateness and Deprescribing Network's 2023 National Meeting.Drug safety · 2024Article
- Deprescribing in older adults in a French community: a questionnaire study on patients' beliefs and attitudes.BMC geriatrics · 2024Article
- Effects from medications on functional biomarkers of aging in three longitudinal studies of aging in Sweden.Aging cell · 2024Article
- Drug-Drug Interactions of Hydroxychloroquine and Chloroquine in Older Patients with COVID-19 during the First Pandemic Waves: The GeroCovid Observational Study.Reports (MDPI) · 2024Article
- Sarcopenia and sarcopenic obesity among older adults in the nordic countries: a scoping review.BMC geriatrics · 2024Article
- Article
- Population-Based Trends in Complexity of Hospital Inpatients.JAMA internal medicine · 2024Article
- The association between continuous polypharmacy and hospitalization, emergency department visits, and death in older adults: a nationwide large cohort study.Frontiers in pharmacology · 2024Article
- Pharmacotherapeutic profile, polypharmacy and its associated factors in a cohort of people living with HIV in Brazil.AIDS research and therapy · 2023Article
- Drug Utilisation Review among Geriatric Patients with Noncommunicable Diseases in a Primary Care Setting in Malaysia.Healthcare (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimPolypharmacy is becoming a global health problem. The aims of this study were to evaluate the temporal trends in the prevalence of polypharmacy in Sweden and to explore polypharmacy disparities by age, gender, education, and immigration status.
methodsPolypharmacy and excessive polypharmacy were evaluated using data extracted from the Swedish Prescribed Drug Register between 2006 and 2014. Polypharmacy was defined as being exposed to five or more drugs and excessive polypharmacy was defined as being exposed to 10 or more drugs during 1 month respectively. Average annual percent change (AAPC) was calculated using Joinpoint Statistical Software.
resultsThe prevalence of polypharmacy increased from 16.9% in 2006 to 19.0% in 2014 with an AAPC of 1.3; the prevalence of excess polypharmacy increased from 3.8% in 2006 to 5.1% in 2014 with an AAPC of 3.4. The prevalence of polypharmacy and excessive polypharmacy increased dramatically with age and peaked up to 79.6% and 36.4% in individuals aged 90 and above respectively. Females and individuals with lower education level were associated with a higher rate of polypharmacy and excessive polypharmacy. Immigrants from Middle-Eastern countries had the highest rate of polypharmacy and excessive polypharmacy, whereas individuals from Western Europe countries had the lowest rate.
conclusionThe prevalence of polypharmacy has increased gradually in Sweden during the past decade. Individuals with older age, female sex, or lower education have a higher rate of polypharmacy and excessive polypharmacy. Immigrants from Middle-Eastern countries showed a higher rate of polypharmacy.
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