ArticleFrontiers in aging neuroscience2020
Fish Intake May Affect Brain Structure and Improve Cognitive Ability in Healthy People.
Article in Frontiers in aging neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Fish consumption and brain structure: a comprehensive systematic review of observational studies.Aging clinical and experimental research · 2026Pooled it
- Dark Chocolate Intake May Reduce Fatigue and Mediate Cognitive Function and Gray Matter Volume in Healthy Middle-Aged Adults.Behavioural neurology · 2022Trial
- Brain condition may mediate the association between training and work engagement.Scientific reports · 2020Trial
- White matter fibers mediate the relationship between workload, resource use, and burnout: a new attempt to apply the conservation of resources theory to neuroscience.Brain structure & function · 2026Article
- Spatiotemporal Patterns of Aquatic Product Risks in China Based on Entropy-Weighted TOPSIS.Foods (Basel, Switzerland) · 2025Article
- Neural Correlates of Eating Habits and Nutritional Behaviors in the General Population: A Systematic Review of Observational Studies.Health science reports · 2025Review
- Examination of the impact of curiosity and fatigue on brain condition.Scientific reports · 2025Article
- Kawaii-Ness Mediates Between Demographic Variables, Happiness, and Brain Conditions.Brain sciences · 2025Article
- Fractional Anisotropy of Cingulum Cingulate Mediates the Relationship Between Happiness and Work Performance in Healthy Individuals.Brain and behavior · 2025Article
- Evaluating the role of ChatGPT in rehabilitation medicine: a narrative review.Frontiers in digital health · 2025Review
- Health benefits of fish and fish by-products-a nutritional and functional perspective.Frontiers in nutrition · 2025Review
- Using three statistical methods to analyze the associations between a mixture of multi-nutrients and risk of mild cognitive impairment in an elderly population in Northern China.Scientific reports · 2024Article
- Effects of sleep deprivation on brain atrophy in individuals with mild cognitive impairment and Alzheimer's disease.Ageing research reviews · 2024Article
- Review
- Smartphone app for lifestyle improvement improves brain health and boosts the vitality and cognitive function of healthy middle-aged adults.Brain and behavior · 2024Article
- Brain conditions mediate the association between aging and happiness.Scientific reports · 2022Article
- The effect of dietary patterns on mild cognitive impairment and dementia incidence among community-dwelling older adults.Frontiers in nutrition · 2022Article
- White matter integrity in delinquent emerging adults and non-delinquent controls, and its relationship with aggression, psychopathic traits, and cannabis use.Frontiers in behavioral neuroscience · 2022Article
- The Personal Trait of Spiritual Growth Is Correlated With the White Matter Integrity of the Brain.Frontiers in human neuroscience · 2022Article
- Can Natural Products Exert Neuroprotection without Crossing the Blood-Brain Barrier?International journal of molecular sciences · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As the population ages worldwide, the prevalence of cognitive disorders including mild cognitive impairment (MCI) is increasing. MCI appears in 10-20% of adults aged 65 years and older and is generally referred to as an intermediate stage between normal cognitive aging and dementia. To develop timely prevention and early treatment strategies by identifying biological factors, we investigated the relationship between dietary consumption of fish, brain structure, and MCI in cognitively normal subjects. The brain structure was assessed using neuroimaging-derived measures including the "gray-matter brain healthcare quotient (GM-BHQ)" and "fractional-anisotropy brain healthcare quotient (FA-BHQ)," which are approved as the international standard (H.861.1) by the International Telecommunication Union Telecommunication Standardization Sector. Dietary consumption of fish was calculated using the brief self-administered diet history questionnaire (BDHQ), and MCI was assessed using the Memory Performance Index (MPI) of MCI screening method (MCI Screen). This study showed that fish intake was positively associated with both FA-BHQ and MPI, and FA-BHQ was more strongly associated with MPI than fish intake. Our findings are in line with those in previous studies, but our study further indicates that the condition of the whole brain integrity measured by the FA-BHQ may mediate the relationship between fish intake and MCI prevention in healthy people. In other words, FA-BHQ may be used to identify people at high risk of MCI to provide the appropriate intervention.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.