ArticleFrontiers in behavioral neuroscience2020
Behavioral Profiling in Early Adolescence and Early Adulthood of Male Wistar Rats After Short and Prolonged Maternal Separation.
Article in Frontiers in behavioral neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Prenatal maternal life adversity impacts on learning and memory in offspring: implication to transgenerational epigenetic inheritance.Frontiers in neuroscience · 2025Article
- Article
- Early life stress influences basal ganglia dopamine receptors and novel object recognition of adolescent and adult rats.IBRO neuroscience reports · 2022Article
- Neurodevelopmental origins of substance use disorders: Evidence from animal models of early-life adversity and addiction.The European journal of neuroscience · 2022Review
- Can the Hole-Board Test Predict a Rat's Exploratory Behavior in a Free-Exploration Test?Animals : an open access journal from MDPI · 2021Article
- The effects of age, sex, and handling on behavioral parameters in the multivariate concentric square field™ test.Physiology & behavior · 2021Article
- The Developmental Origins of Opioid Use Disorder and Its Comorbidities.Frontiers in human neuroscience · 2021Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Early-life stress and its possible correlations to genes, environment, and later health outcomes can only be studied retrospectively in humans. Animal models enable the exploration of such connections with prospective, well-controlled study designs. However, with the recent awareness of replicability issues in preclinical research, the reproducibility of results from animal models has been highlighted. The present study aims to reproduce the behavioral effects of maternal separation (MS) previously observed in the multivariate concentric square field
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.