Evidence map›Paper›PMID 32265521›Full record

ArticleNature reviews. Nephrology2020

Diagnoses of uncertain significance: kidney genetics in the 21st century.

Daniel P Gale, Andrew Mallett, Chirag Patel, Tam P Sneddon, Heidi L Rehm, Matthew G Sampson, Detlef Bockenhauer

Abstract read
PubMed Publisher
In one paragraph

Article in Nature reviews. Nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Fifty Shades of Risk: Population Studies and the Genetic Architecture of Kidney Diseases.Journal of the American Society of Nephrology : JASN · 2026
    Review
  3. Article
  4. Article
  5. Ascertaining pathogenicity of genetic variants: caution required.Pediatric nephrology (Berlin, Germany) · 2023
    Article
  6. Article
  7. SLC26A1 is a major determinant of sulfate homeostasis in humans.The Journal of clinical investigation · 2023
    Article
  8. A practical approach to the genomics of kidney disorders.Pediatric nephrology (Berlin, Germany) · 2022
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel P GaleDepartment of Renal Medicine, University College London, London, UK.ORCID http://orcid.org/0000-0002-9170-1579
Andrew MallettKidGen Collaborative, Australian Genomics Health Alliance, Parkville, Victoria, Australia.
Chirag PatelKidGen Collaborative, Australian Genomics Health Alliance, Parkville, Victoria, Australia.
Tam P SneddonDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.ORCID http://orcid.org/0000-0003-1137-8992
Heidi L RehmCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6025-0015
Matthew G SampsonMedical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA. matthew.sampson@childrens.harvard.edu.ORCID http://orcid.org/0000-0001-9560-076X
Detlef BockenhauerDepartment of Renal Medicine, University College London, London, UK. d.bockenhauer@ucl.ac.uk.ORCID http://orcid.org/0000-0001-5878-941X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Precision MedicineGenetics, MedicalGenetic TestingGenetic VariationGenomicsHumansKidney DiseasesNephrologyProbabilityUncertainty

Identifiers

PMID32265521

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.