Evidence map›Paper›PMID 32265328›Full record

ArticlemBio2020

Histidine-Triad Hydrolases Provide Resistance to Peptide-Nucleotide Antibiotics.

Eldar Yagmurov, Darya Tsibulskaya, Alexey Livenskyi, Marina Serebryakova, Yury I Wolf, Sergei Borukhov, Konstantin Severinov, Svetlana Dubiley

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Eldar YagmurovCenter for Life Sciences, Skolkovo Institute of Science and Technology, Skolkovo, Russia.
Darya TsibulskayaCenter for Life Sciences, Skolkovo Institute of Science and Technology, Skolkovo, Russia.
Alexey LivenskyiInstitute of Gene Biology, Russian Academy of Science, Moscow, Russia.
Marina SerebryakovaInstitute of Gene Biology, Russian Academy of Science, Moscow, Russia.
Yury I WolfNational Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, USA.ORCID 0000-0002-0247-8708
Sergei BorukhovDepartment of Cell Biology and Neuroscience, Rowan University School of Osteopathic Medicine, Stratford, New Jersey, USA.
Konstantin SeverinovCenter for Life Sciences, Skolkovo Institute of Science and Technology, Skolkovo, Russia severik@waksman.rutgers.edu svetlana.dubiley@gmail.com.
Svetlana DubileyCenter for Life Sciences, Skolkovo Institute of Science and Technology, Skolkovo, Russia severik@waksman.rutgers.edu svetlana.dubiley@gmail.com.
Skolkovo Institute of Science and Technology · RULomonosov Moscow State University · RUNational Center for Biotechnology Information · USRowan University · US

Funding

Exploring Peptide Conjugates as Trojan Horse Systems for Drug Design and DiscoveryR01AI117210 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI NAIR, SATISH K · 2016 to 2020
$2.2M
NIAID NIH HHS R01 AI117210
6 · The paper itself

Abstract

The

Indexed as

Multigene FamilyAnti-Bacterial AgentsBacterial ProteinsBacteriocinsBiosynthetic PathwaysDrug Resistance, BacterialEscherichia coliHydrolasesMyxococcalesOperonPeptidesAnti-Bacterial AgentsBacterial ProteinsBacteriocinshistidine triad proteinHydrolasesmicrocinPeptidesantibioticsHinThistidine-triad proteinsmicrocin Cpeptide-nucleotidesRiPPs

Identifiers

PMID32265328
PMCPMC7157772
OpenAlexW3014427446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.