Evidence map›Paper›PMID 32265282›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Mapping the

Timothy J Cherry, Marty G Yang, David A Harmin, Peter Tao, Andrew E Timms, Miriam Bauwens, Rando Allikmets, Evan M Jones, Rui Chen, Elfride De Baere and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 2 syntheses or guidelines pooled it, 116 citations in OpenAlex.

  1. Pooled it
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  17. Non-coding single-nucleotide and structural variants affecting the EYS putative promoter cause autosomal recessive retinitis pigmentosa.Genetics in medicine : official journal of the American College of Medical Genetics · 2025
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20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Timothy J CherryDepartment of Pediatrics, University of Washington School of Medicine, Seattle, WA 98101; timothy.cherry@seattlechildrens.org michael_greenberg@hms.harvard.edu.ORCID 0000-0003-1532-9856
Marty G YangDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.ORCID 0000-0001-5788-3092
David A HarminDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Peter TaoDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115.
Andrew E TimmsCenter for Developmental Biology and Regenerative Medicine, Seattle Children's Research Institute, Seattle, WA 98101.ORCID 0000-0002-8808-4012
Miriam BauwensCenter for Medical Genetics, Ghent University and Ghent University Hospital, 9000 Ghent, Belgium.
Rando AllikmetsDepartment of Ophthalmology, Columbia University, New York, NY 10032.ORCID 0000-0002-3344-4447
Evan M JonesHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030-3411.
Rui ChenHuman Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030-3411.
Elfride De BaereCenter for Medical Genetics, Ghent University and Ghent University Hospital, 9000 Ghent, Belgium.
Michael E GreenbergDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115; timothy.cherry@seattlechildrens.org michael_greenberg@hms.harvard.edu.ORCID 0000-0003-1380-2160
Harvard University · USBaylor College of Medicine · USGhent University Hospital · BESeattle Children's Hospital · USColumbia University · US

Funding

Instrumentation, Fabrication, and Design CoreP30EY019007 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Xin Zhang · 2010 to 2026
$12.9M
ELECTRICAL STIMULATION OF IMMEDIATE EARLY GENESR37NS028829 · NINDS · HARVARD MEDICAL SCHOOL · PI GREENBERG, MICHAEL ELDON · 1999 to 2019
$7.4M
Non-Coding Genetic Vulnerabilities in Human Photoreceptor Function and DiseaseR01EY028584 · NEI · SEATTLE CHILDREN'S HOSPITAL · PI CHERRY, TIMOTHY JOEL · 2019 to 2025
$4.2M
Integrated clinical, genetic and functional analysis of the ABCA4 locusR01EY029315 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ALLIKMETS, RANDO L · 2019 to 2023
$2.2M
NEI NIH HHS P30 EY019007NEI NIH HHS R01 EY028584NEI NIH HHS R01 EY029315NINDS NIH HHS R37 NS028829
6 · The paper itself

Abstract

The interplay of transcription factors and

Indexed as

Evolution, MolecularGene Expression Regulation, DevelopmentalAdultAnimalsDNA Mutational AnalysisEpigenomicsFemaleGenetic VariationHumansMaleMiceMiddle AgedMutationRegulatory Sequences, Nucleic AcidRetinaRetinal Diseasescis-regulatory elementenhancerhumannoncodingretina

Identifiers

PMID32265282
PMCPMC7183164
OpenAlexW3015016698

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.