Evidence map›Paper›PMID 32264961›Full record

ArticleHealth and quality of life outcomes2020

Validation of the Chinese EORTC chronic lymphocytic leukaemia module - application of classical test theory and item response theory.

Dong Dong, Jun Jin, Simone Oerlemans, Siyue Yu, Shenmiao Yang, Jianfeng Zhu, Richard Huan Xu

Open access · goldAbstract readValidation Study
In one paragraph

Article in Health and quality of life outcomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Dong DongJC School of Public Health & Primary Care, The Chinese University of Hong Kong, Hong Kong, SAR, China.
Jun JinDepartment of Sociology, School of Social Sciences, Tsinghua University, Beijing, China.
Simone OerlemansNetherlands Comprehensive Cancer Organization, Eindhoven, Netherlands.
Siyue YuJC School of Public Health & Primary Care, The Chinese University of Hong Kong, Hong Kong, SAR, China.
Shenmiao YangPeking University Institute of Hematology, Peking University People's Hospital, Beijing, China.
Jianfeng ZhuSchool of Social Development and Public Policy, Fudan University, Shanghai, China. jfzhu@fudan.edu.cn.
Richard Huan XuJC School of Public Health & Primary Care, The Chinese University of Hong Kong, Hong Kong, SAR, China. richardhxu@cuhk.edu.hk.
Chinese University of Hong Kong · CNFudan University · CNNetherlands Comprehensive Cancer Organisation · NLPeking University · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe association of chronic lymphocytic leukemia (CLL) with health-related quality of life (HRQoL) is rarely studied globally. This study evaluated the psychometric properties of the EORTC-Chronic Lymphocytic Leukaemia (CLL17 [phase III]) module, a newly developed assessment on CLL patients' HRQoL, among Chinese CLL patients.

methodsThe Chinese CLL17, comprised of three subscales (symptom burden [SB], physical condition [PC] and worries/fears [WF]), was provided by the developer team through EORTC. A cross-sectional online survey was conducted to collect data. The classical traditional theory (CTT) and the item response theory (IRT) were used to evaluate the psychometric properties of CLL17. Internal consistency reliability was determined by the Cronbach's alpha and item-total correlation. Dimensionality was verified through confirmatory factor analysis (CFA). Convergent validity was also assessed. The generalized partial credit model was used for the IRT. The difficulty, discrimination, item fit, and differential item functioning (DIF) were calculated to assess the instrument's psychometric properties.

resultsIn all, 318 patients, aged between 26 and 82 years, completed the questionnaire. A good level of internal reliability was achieved (Cronbach's alpha = 0.92). The item-total correlation coefficient ranged from 0.46 to 0.72. There was a mid-to-high correlation between CLL17 and domains of EQ-5D and QLQ-C30. The IRT model showed a satisfactory homogeneity, item fit and good discrimination of items, except for item 4, 6 and 16 (< 1.0). low information provided by item 16 and 17. SB and PC provided more information with theta > 0, whereas WF provided more information with theta < 0. Item 17 perform inconsistently for respondents from different age groups (DIF).

conclusionThe EORTC-CLL17 Chinese version shows acceptable reliability and validity, making it a valuable instrument to evaluate the impact on the HRQoL of Chinese CLL patients.

Indexed as

Quality of LifeAdultAgedAged, 80 and overCross-Sectional StudiesFactor Analysis, StatisticalFemaleHumansLeukemia, Lymphocytic, Chronic, B-CellMaleMiddle AgedReproducibility of ResultsSurveys and QuestionnairesChinaChronic lymphocytic leukaemiaEORTC-CLL17Health-related quality of life (HRQoL)Item response theoryPsychometrics

Identifiers

PMID32264961
PMCPMC7137502
OpenAlexW3014546737

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.